五色营养与微生态协同的东方轻断食营养策略研究OA

[Objective]Explore the synergistic mechanism between the five-colourand five-element nutritional theory of traditional Chinese medicine and modern light fasting,construct a nutritional model of meal replace-ment that is suitable for the physique of East Asians,and provide a theoretical basis for the development of functional meal replacement products with both cultural compatibility and scientific validity.[Method]The keywords"five-colour and five-element nutrition theory","Intermittent fasting","meal replacement","Traditional Chinese Medicine Constitution"and"intestinal flora"were used to analyse the multi-target effects of five-colour food active ingredients and the effect of light fasting intervention."intestinal flora"as the keywords,we systematically searched the relevant literature,combined the evidence of metabolomics and nutrigenomics,and analysed the multi-targeting effects of the five-colour food active ingredients and the effect of light fasting intervention.[Result]Based on the Five-Element Theory from The Yellow Emperor's Inner Canon,a functional mapping between the five colors(green/red/yellow/white/black)and the five zang-organs(liver/heart/spleen/lung/kidney)has been established.Modern research confirms that phytonutrients in five-color foods(e.g.,quercetin,lycopene)target the regulation of lipid peroxidation,the AMPK/PPARγ axis,and gut microbiota structure,significantly enhancing the body's tolerance to intermittent fasting regimens and synergisti-cally optimizing their glucolipid metabolic improvement effects.An innovative"Oriental Intermittent Fasting"model is proposed,integrating"time-restricted eating,five-color nutrition,constitution identification,and microecological regulation."This model aims to optimize metabolic indicators for specific constitution patterns such as phlegm-dampness and yang-deficiency,and has preliminarily validated dynamic correlations between the five-color theoretical framework and metabolomic markers(e.g.,tryptophan).[Conclusion]It provides a novel theoretical framework and approach for the development of meal replacement products tailored for East Asian populations.However,further research is needed regarding long-term safety,precise dosing,and the elucidation of molecular mechanistic networks.