日粮添加丁酸梭菌对肉鸡生长性能、血清指标和肠道健康指标的影响OA

This study aimed to explore the effects of dietary supplementation with clostridium butyricum on the growth performance,serum index and intestinal health indicators of Arbor Acres broilers.A total of 400 1-day-old Arbor Acres broilers with an average body weight of 42.57±1.41 g were selected and randomly divided into 4 groups,with 10 replicates in each group and 10 Arbor Acres broilers in each replicate.The control group was fed a basal diet,and 0.2%,0.4%and 0.6%clostridium butyricum(2.88×109 CFU/g)were added to the basal diet in trial groups Ⅰ,Ⅱ and Ⅲ,respectively.The experiment lasted for 45 days.The results showed that:(1)compared with the control group and the trial groupⅠ,the average daily feed intake and average daily weight gain of the trial group Ⅱ were significantly increased(P<0.05),and feed-to-gain ratio was significantly decreased(P<0.05).(2)Compared with the control group and the trial group I,the serum catalase,total cholesterol,triglycerides,and low-density lipoprotein in the trial group Ⅱ were all lower(P<0.05),while the serum total superoxide dismutase,high-density lipoprotein,immunoglobulin A,and immunoglobulin M were all higher(P<0.05).(3)Compared with the control group and the trial group I,villus height and villus height/crypt depth were significantly increased(P<0.05),while crypt depth was significantly decreased(P<0.05),the relative mRNA expression levels of Claudin-1 and Zonula Occludens-1 in the trial group Ⅱwere significantly increased(P<0.05).In conclusion,dietary supplementation of 0.4%clostridium butyricum can improve growth performance and optimize the serum and intestinal health indicators of broilers.