Brain organoids and genome editing:A new era in understanding human brain development and disordersOA
Brain organoids and genome editing:A new era in understanding human brain development and disorders
Min Zhou;Zhenzhou Li;Huan Wang;Zhengliang Gao;Yuanqing Cao;Ke Yue;Wenyu Wu;Yutong Xie;Daiyu Hu;Jingjing Zhao;Fang Xu;Jianrong Guo
Clinical Research Center for Mental Health,Mental Health Center Affiliated to School of Medicine(Shanghai Hongkou Mental Health Center),Shanghai University,Shanghai,China||Department of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China||Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,ChinaDepartment of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,ChinaDepartment of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,ChinaDepartment of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,China||Fundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China||China-Japan Friendship Medical Research Institute,School of Medicine,Shanghai University,Shanghai,ChinaFundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China||School of Basic Medicine,Medical Genetics and Cell Biology,Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,ChinaClinical Research Center for Mental Health,Mental Health Center Affiliated to School of Medicine(Shanghai Hongkou Mental Health Center),Shanghai University,Shanghai,China||Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,ChinaClinical Research Center for Mental Health,Mental Health Center Affiliated to School of Medicine(Shanghai Hongkou Mental Health Center),Shanghai University,Shanghai,China||Department of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China||Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,ChinaFundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China||School of Basic Medicine,Medical Genetics and Cell Biology,Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,ChinaFundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China||School of Basic Medicine,Medical Genetics and Cell Biology,Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,ChinaClinical Research Center for Mental Health,Mental Health Center Affiliated to School of Medicine(Shanghai Hongkou Mental Health Center),Shanghai University,Shanghai,China||Department of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,China||Department of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,ChinaSchool of Basic Medicine,Medical Genetics and Cell Biology,Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,ChinaDepartment of Anesthesiology,Gongli Hospital of Shanghai Pudong New Area,Shanghai,China
brain disorderbrain organoidCRISPR/Cas9disease modelingdrug screeninggenome editinghuman brain developmentlineage tracingorganoid modelingstem cell differentiation
brain disorderbrain organoidCRISPR/Cas9disease modelingdrug screeninggenome editinghuman brain developmentlineage tracingorganoid modelingstem cell differentiation
《中国神经再生研究（英文版）》 2026 (7)
2761-2771,11
This work was supported by the Special Project for Clinical Research of Shanghai Municipal Health Commission,No.202140403(to HW)Key Disciplines Group Construction Project of Pudong Health Bureau of Shanghai,No.PWZxq 2022-05(to JG)Natural Science Foundation of Ningxia Hui Autonomous Region,No.2024AAC05084(to ZL)Ningxia Hui Autonomous Region Key Research and Development Program,No.2021BEG03084(to FX)and National Natural Science Foundation of China,Nos.32370895 and 32070862(both to ZG).
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