两种单侧经皮穿刺椎体后凸成形术治疗单节段胸腰段骨质疏松椎体压缩骨折的疗效比较OA
Comparison of the efficacy of two unilateral percutaneous translaminar vertebral kyphoplasty procedures for the treatment of single-segment thoracolumbar osteoporotic vertebral compression fractures
目的:探讨经皮弯曲椎体成形术(percutaneous curve kyphoplasty,PCKP)与单侧椎体后凸成形术(unilater-al kyphoplasty,UPKP)在胸腰段骨质疏松椎体压缩骨折(osteoporotic vertebral compression fractures,OVCF)治疗中的临床疗效差异,重点评估骨水泥分布、渗漏风险及椎体生物力学恢复效果.方法:纳入2022年1月至2024年4月收治的78例急性胸腰段OVCF患者,根据手术方法分为PCKP组37例与UPKP 组 41例.PCKP组37例,男12例,女25例,年龄(78.84±11.24)岁,骨密度T值-4.05±0.81;UPKP组41例,男17例,女24例,年龄(77.68±10.73)岁,骨密度T值-4.15±0.82.比较两组术前及术后疼痛视觉模拟评分(visual analogue scale,VAS)、Oswestry功能障碍指数(Oswestry disability index,ODI)、椎体前柱高度、骨水泥分布优良率、渗漏率及手术相关指标.结果:两组患者随访时间12个月,PCKP 组 VAS 评分在术前及术后 2d 和术后 3、12 个月分别为(6.35±2.34)、(2.95±0.70)、(1.76±1.19)、(0.97±0.80)分,UPKP 组分别为(6.83±2.23)、(3.15±0.82)、(1.73±1.12)、(1.17±0.74)分.PCKP 组 ODI 评分在术前及术后 2 d 和术后 3、12 个月分别为(75.73±3.42)、(34.57±3.18)、(24.03±5.24)、(22.84±1.68)分,UPKP 组分别为(74.41±2.85)、(35.54±3.49)、(24.95±2.85)、(22.66±1.70)分.两组术后VAS、ODI评分均显著改善(P<0.05),但组间比较差异无统计学意义(P>0.05).PCKP组骨水泥分布优良率为91.89%(34/37),高于UPKP组65.85%(27/41),两组比较差异有统计学意义(P=0.001);PCKP组渗漏率为13.51%(5/37),优于UPKP组34.15%(14/41),两组比较差异有统计学意义(P=0.030).两组骨水泥不良分布者和渗漏者椎体压缩程度比较,差异无统计学意义(P>0.05).PCKP组椎体前柱高度术前(13.22±2.47)mm,术后 2d(16.68±1.42)mm;UPKP 组术前(13.80±2.50)mm,术后 2 d(17.02±1.35)mm;两组术后 2 d 椎体前柱高度均较术前显著恢复(P<0.05),但组间比较差异无统计学意义(P>0.05).PCKP组再骨折4例,UPKP组6例,两组比较差异无统计学意义(P>0.05).两组手术时间及透视次数比较,差异均无统计学意义(P>0.05).结论:PCKP通过弧形骨钻技术优化骨水泥双侧弥散,显著提升分布均匀性并降低渗漏风险,尤其适用于中重度压缩骨折;其单侧穿刺、低压灌注的技术特点在不增加手术时间与辐射暴露的前提下,为胸腰段OVCF提供了更安全有效的微创解决方案.未来需扩大样本量并延长随访以验证其远期生物力学优势.
Objective To investigate the differences in clinical efficacy between percutaneous curved kyphoplasty(PCKP)and unilateral percutaneous kyphoplasty(UPKP)in the treatment of thoracolumbar osteoporotic vertebral compression fractures(OVCF),with a focus on evaluating cement distribution,leakage risk,and vertebral biomechanical restoration.Methods A to-tal of 78 patients with acute thoracolumbar OVCF admitted between January 2022 and April 2024 were included.They were divided into a PCKP group and a UPKP group based on the surgical technique.The PCKP group comprised 37 cases,including 12 males and 25 females,with an age of(78.84±11.24)years and a bone mineral density T value of-4.05±0.81.The UPKP group included 41 cases,comprising 17 males and 24 females,with an age of(77.68±10.73)years and a bone mineral density T value of-4.15±0.82.Comparisons were made between the two groups regarding preoperative and postoperative visual ana-logue scale(VAS)pain scores,Oswestry disability index(ODI)scores,anterior vertebral body height,rate of good/excellent cement distribution,cement leakage rate,and surgery-related parameters.Results All patients were followed up for 12 months.In the PCKP group,the mean VAS preoperatively,and at 2 days,3 months,and 12 months postoperatively were(6.35±2.34),(2.95±0.70),(1.76±1.19),and(0.97±0.80)points,respectively.Corresponding scores in the UPKP group were(6.83±2.23),(3.15±0.82),(1.73±1.12),and(1.17±0.74)points.The mean ODI scores in the PCKP group at the same time points were(75.73±3.42),(34.57±3.18),(24.03±5.24),and(22.84±1.68)points,respectively,compared to(74.41±2.85),(35.54±3.49),(24.95±2.85),and(22.66±1.70)points in the UPKP group.Both groups showed significant improvement in VAS and O-DI scores postoperatively(P<0.05),but no statistically significant differences were observed between the groups(P>0.05).The rate of good/excellent cement distribution in the PCKP group was 91.89%(34/37),significantly higher than the 65.85%(27/41)in the UPKP group(P=0.001).The cement leakage rate was 13.51%(5/37)in the PCKP group,which was significantly lower than the 34.15%(14/41)in the UPKP group(P=0.030).No significant difference was found in the degree of vertebral compression between patients with poor cement distribution/leakage and those without in either group(P>0.05).The mean ante-rior vertebral body height in the PCKP group increased from(13.22±2.47)mm preoperatively to(16.68±1.42)mm at 2 days postoperatively.In the UPKP group,it increased from(13.80±2.50)mm to(17.02±1.35)mm at 2 days postoperatively.Both groups showed significant restoration of anterior vertebral height postoperatively(P<0.05),with no significant intergroup differ-ence(P>0.05).Re-fractures occurred in 4 cases in the PCKP group and 6 cases in the UPKP group,showing no significant in-tergroup difference(P>0.05).No significant differences were found in operative time or fluoroscopy frequency between the two groups(P>0.05).Conclusion PCKP,utilizing a curved drill technique,optimizes bilateral cement dispersion,significantly im-proving distribution uniformity and reducing leakage risk,making it particularly suitable for moderate-to-severe compression fractures.Its technical characteristics such as unilateral puncture and low-pressure cement infusion-provide a safer and more effective minimally invasive solution for thoracolumbar OVCF without increasing operative time or radiation exposure.Future studies with larger sample sizes and longer follow-up are needed to verify its long-term biomechanical advantages.
杨富国;罗园超;陈康;何仁建
自贡市第一人民医院骨科,四川自贡 643000自贡市第一人民医院骨科,四川自贡 643000自贡市第一人民医院骨科,四川自贡 643000自贡市第一人民医院骨科,四川自贡 643000
医药卫生
骨质疏松性骨折椎体后凸成形术脊柱骨折骨水泥治疗结果
Osteoporotic fracturesKyphoplastySpinal fracturesBone cementsTreatment outcome
《中国骨伤》 2026 (2)
130-137,8
自贡市科学技术局重点研发项目(编号:ZC202001)Zigong Science and Technology Bureau Key R&D Project(No.2020ZC01)
评论