湖羊FecB基因多态性与产羔数和羔羊早期生长发育的关联分析OA

To investigate the polymorphism and inheritance pattern of the FecB gene in adult Hu sheep ewes,analyze the relationship between genotype and lambing performance,and evaluate the impact of genotype on the growth and de-velopment of Hu sheep lambs and W×H(Wugu sheep♂×Hu sheep ♀)F1 crossbred lambs,this study employed the SNaPshot high-throughput genotyping technique to genotype the FecB gene in adult Hu sheep,Hu sheep lambs,and W×H F1 crossbred lambs from a Hu sheep breeding farm in Taizhou,Jiangsu province.The distribution of the FecB gene in the sheep population was statistically analyzed.Combined with the lambing data of adult Hu sheep ewes and the body measurement and weight data of lambs at birth,2 months and 6 months of age,the correlation between the FecB gene and lambing number in adult Hu sheep ewes as well as early growth and development was examined.The re-sults showed that the FecB gene in adult Hu sheep ewes exhibited three genotypes GG,AG,and AA.The lambing rate of GG genotype ewes was significantly higher than that of AG genotype ewes(P<0.01).In the Hu sheep lamb popula-tion,the FecB gene had two genotypes GG and AG.The GG genotype individuals had significantly lower weight,body height,body length,and cannon bone circumference than the AG genotype lambs at birth(P<0.05).At 2 months of age,the GG genotype individuals also had significantly lower body weight,body height,body length,and chest circumfer-ence than the AG genotype lambs(P<0.05).However,no significant differences were observed in body weight,body height,body length,chest circumference,or cannon bone circumference between the two genotypes at 6 months of age lambs(P>0.05).In the W×H F1 crossbred lamb population,the FecB gene had two genotypes:AG and AA.The AG genotype individuals had significantly lower birth weight and body measurements than the AA genotype lambs(P<0.05).At 2 months of age,the AG genotype individuals also had significantly lower body weight and body height than the AA genotype lambs(P<0.05).However,no significant differences were observed in body weight and body measure-ments between the two genotypes lambs at 6 months of age(P>0.05).In conclusion,the FecB gene is a major gene in-fluencing the lambing rate in Hu sheep and is associated with early growth traits in both Hu sheep and W×H crossbred lambs.The influence of the FecB gene on lamb growth and development tends to diminish as the lambs mature.