不稳定型心绞痛患者PCI术后并发心力衰竭的危险因素及干预对策分析OA
Analysis of Risk Factors for Heart Failure After PCI in Patients with Unstable Angina Pectoris and Corresponding Intervention Strategies
目的 分析不稳定型心绞痛(UAP)患者经皮冠状动脉介入治疗(PCI)术后并发心力衰竭(HF)的危险因素与干预对策.方法 回顾性选取 2021 年 1 月至 2023 年 12 月期间于河南科技大学第一附属医院接受PCI手术的 120 例UAP患者临床资料,依据患者PCI术后是否发生HF分为发生组(n=23)与未发生组(n=97).收集患者临床信息,并对研究对象存在差异的指标展开Logistic回归分析,分析影响UAP患者PCI术后发生HF的危险因素,并探讨干预对策.结果 本研究共纳入 120例UAP患者,其中 23例患者在接受PCI术后出现HF,发生率为 19.17%.经单因素分析发现,发生组匹兹堡睡眠质量指数量表(PSQI)评分、D-二聚体(D-D)、肿瘤坏死因子α(TNF-α)以及是否合并糖尿病与未发生组存在差异(P<0.05).差异项目经Logistic回归方程计算,结果发现PSQI评分、D-D、TNF-α以及合并糖尿病是影响UAP患者在PCI术后出现HF的危险因素,OR值>1.结论 PSQI评分、D-D、TNF-α以及合并糖尿病均可影响UAP患者PCI术后发生HF,通过上述因素筛查出高危群体,可便于临床展开针对性干预对策.
Objective To analyze the risk factors for heart failure(HF)after percutaneous coronary intervention(PCI)in patients with unstable angina pectoris(UAP)and to explore corresponding intervention strategies.Methods The clinical data of 120 patients with UAP who underwent PCI at The First Affiliated Hospital of Henan University of Science and Technology from January 2021 to December 2023 were retrospectively collected.According to whether HF occurred after PCI,the patients were divided into an HF group(n=23)and a non-HF group(n=97).Clinical data were collected,and the variables that showed significant differences between the two groups were included in Logistic regression analysis to identify the risk factors for HF after PCI in patients with UAP and to explore intervention strategies.Results A total of 120 patients with UAP were included in this study,among whom 23 developed HF after PCI,with an incidence of 19.17%.Univariate analysis showed that the Pittsburgh Sleep Quality Index(PSQI)score,D-dimer(D-D),tumor necrosis factor-α(TNF-α),and the presence of diabetes mellitus differed significantly between the HF group and the non-HF group(P<0.05).Logistic regression analysis of these variables showed that the PSQI score,D-D,TNF-α,and concomitant diabetes mellitus were risk factors for HF after PCI in patients with UAP,with odds ratios(OR)>1.Conclusion The PSQI score,D-D,TNF-α,and concomitant diabetes mellitus can all affect the occurrence of HF after PCI in patients with UAP.Screening high-risk populations based on these factors may facilitate the implementation of targeted clinical intervention strategies.
刘月;李欢欢;赵毅
河南科技大学第一附属医院 心脏内科,河南 洛阳 471000河南科技大学第一附属医院 肿瘤科,河南 洛阳 471000河南科技大学第一附属医院 心脏内科,河南 洛阳 471000
不稳定型心绞痛经皮冠状动脉介入治疗心力衰竭干预对策
unstable angina pectorispercutaneous coronary interventionheart failureintervention strategies
《临床研究》 2026 (3)
10-13,4
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