NLR、TBil、CRP与2型糖尿病外周动脉病变的相关性OA

Objective To investigate the correlation between neutrophil lymphocyte count ratio(NLR),total bilirubin(TBil),C-reactive protein(CRP)and peripheral arterial disease in type 2 diabetes(T2DM).Methods A retrospective study was conducted on 183 T2DM patients admitted to Luoyang Central Hospital from February 2019 to October 2022.They were divided into a control group and an observation group based on whether peripheral arterial lesions occurred.The control group(97 cases)had simple T2DM,while the observation group(86 cases)had T2DM combined with peripheral arterial lesions.Compare the levels of two related indicators,influencing factors of peripheral arterial lesions in T2DM,diagnostic value,and correlation.Results The age of patients in the observation group,the proportion of patients with underlying diseases,the proportion of insulin use,the level of peripheral blood NLR and serum CRP were higher than those in the control group,the level of peripheral blood TBil was lower than that in the control group,and the course of diabetes was longer than that in the control group,with statistically significant differences(P＜0.05);Age,NLR,TBil,and CRP are all influencing factors of peripheral arterial lesions in T2DM(P＜0.05);The AUC value of the combined diagnosis of T2DM peripheral arterial lesions by various indicators was higher than that of single detection,and the difference was statistically significant(P＜0.05);Peripheral blood NLR(r=0.486)and serum CRP(r=0.571)were positively correlated with peripheral arterial lesions in T2DM(P＜0.05),while peripheral blood TBil(r=-0.534)was negatively correlated with peripheral arterial lesions in T2DM(P＜0.05).Conclusion There is a correlation between age,NLR,TBil,CRP and peripheral arterial lesions in T2DM,and the discriminatory ability of combined indicators is better than that of single indicators.