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"智""镜"联合——探索慢性胃炎的中西医诊断与辨证OA

Exploring the diagnosis and syndrome differentiation of chronic gastritis with Chinese and Western medicine based on machine learning and gastroscopy

中文摘要英文摘要

目的 探索多种机器学习模型基于胃镜下胃黏膜状态预测慢性胃炎(CG)的分类诊断与分型辨证,为中西医诊断理论创新提供价值.方法 回顾性收集诊断为慢性胃炎的2052张胃镜图像,进行数据预处理后,建立3种机器学习模型,评估机器学习算法辅助下胃镜在慢性胃炎诊断中的价值.胃镜作为中医望诊的延伸,在原有数据中筛选2016张胃镜图像作为新的数据集,基于机器学习进行虚实辨证,探索胃镜在慢性胃炎中医辨证分型中的作用.结果 训练的3种基于胃镜的模型(ViT、ResNet50、VGG16)对慢性萎缩性胃炎(CAG)的准确率分别 98.60%、95.16%、95.81%,识别慢性非萎缩性胃炎(CNAG)准确率依次为99.16%、99.58%、99.16%;进一步实验的4种机器学习模型(ViT、ResNet50、VGG16、Mobilenet)识别CG实证组准确率依次为95.09%、88.24%、90.20%、87.25%;CG虚证组准确率为:89.10%、88.11%、89.14%、91.09%.结论 机器学习可以作为辅助CG胃镜下诊断的稳定方法,且将课题组开发的基于胃镜的机器学习诊断模型可用于CG的中医虚实辨证.机器学习可辅助医师对该病进行识分类、辨证等任务,为人机共同决策提供临床应用价值.

Objective To explore the classification diagnosis and syndrome differentiation of chronic gastritis(CG)based on various machine learning models using gastroscopic images,and to assess its value for theoretical innovation in the diagnosis of Chinese and Western medicine.Methods From June 2023 to March 2024,2,052 gastroscopic images from patients diagnosed with CG were retro-spectively collected at Hebei Provincial Hospital of Traditional Chinese Medicine.After data preprocessing,three machine learning models were established to evaluate the value of machine learning-assisted gastroscopy for diagnosing CG.As an supplement of tradi-tional Chinese medicine(TCM)inspection,gastroscopy was utilized.From the original dataset,2016 gastroscopic images were selected to form a new dataset.Based on machine learning,deficiency-excess syndrome differentiation was performed to explore the role of gas-troscopy in TCM syndrome differentiation of CG.Results The accuracy rates of the three gastroscopy-based models(ViT,ResNet50,VGG16)we trained for chronic atrophic gastritis(CAG)were 98.60%,95.16%,and 95.81%,respectively.For chronic non-atrophic gastritis(CNAG),the accuracies were 99.16%,99.58%,and 99.16%,respectively.In further experiments,the four machine learn-ing models(ViT,ResNet50,VGG16,MobileNet)achieved accuracies of 95.09%,88.24%,90.20%,and 87.25%for identifying the CG excess syndrome group,and 89.10%,88.11%,89.14%,and 91.09%for the CG deficiency syndrome group,respectively.Con-clusion This study demonstrates that machine learning can serve as a reliable method to assist in the gastroscopic diagnosis of CG.Fur-thermore,the gastroscopy-based machine learning diagnostic model we developed can be used for TCM syndrome differentiation of CG.Machine learning can assist physicians in disease classification and syndrome differentiation,offering clinical value for human-computer collaborative decision-making.

段雨萌;于倩茹;张柳盟;康丽洁;张坤;支政;杨倩;徐伟超

河北省中医院,河北 石家庄 050011||河北中医药大学研究生院,河北 石家庄 050011河北科技大学信息科学与工程学院,河北 石家庄 050018河北省中医院,河北 石家庄 050011||河北中医药大学研究生院,河北 石家庄 050011河北省中医院,河北 石家庄 050011河北科技大学信息科学与工程学院,河北 石家庄 050018河北省中医院,河北 石家庄 050011||河北中医药大学研究生院,河北 石家庄 050011河北中医药大学研究生院,河北 石家庄 050011||河北省浊毒证重点实验室,河北 石家庄 050011河北省中医院,河北 石家庄 050011||河北中医药大学研究生院,河北 石家庄 050011||河北省浊毒证重点实验室,河北 石家庄 050011

医药卫生

慢性胃炎机器学习胃镜下辨证Vision TransformerResNet50

Chronic gastritisMachine learningGastroscopic syndrome differentiationVision transformerResNet50

《时珍国医国药》 2026 (5)

993-1000,8

国家自然科学基金(82205314)癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项(2024ZD0521004)中华中医药学会脾胃病分会青年培英计划(中会学术[2025]2号)河北省省级科技计划资助项目(246W7701D)河北省"岐黄赤子"培养工程(冀中医药函[2025]1号)河北省高等教育教学改革研究与实践项目(2023GJJG287)

10.70976/j.1008-0805.SZGYGY-2026-0529

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