Rapid Discovery,Guided Isolation,and Mechanism Study of Anti-neuroinflammatory Constituents from Glycosmis craibii var.glabra Targeting 5-LOXOA
Rapid Discovery,Guided Isolation,and Mechanism Study of Anti-neuroinflammatory Constituents from Glycosmis craibii var.glabra Targeting 5-LOX
Hong-Wei Chen;Peng-Fei Tu;Yong Jiang;Meng Ding;Shi-Zhong Chen;Wang-Xiao Tan;Jun Lin;Shuo Yuan;Yi-Chi Zhang;Xin-Nuo Tong;Ke-Wu Zeng
State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,ChinaState Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences Department of Natural Medicines,Peking University,Beijing 100191,China
5-LOX inhibitor5-LOX/CysLT1R pathwayanti-neuroinflammationGlycosmis craibii var.glabraonline UPLC-PDA-5-LOX-FLD system
5-LOX inhibitor5-LOX/CysLT1R pathwayanti-neuroinflammationGlycosmis craibii var.glabraonline UPLC-PDA-5-LOX-FLD system
《世界中医药杂志（英文版）》 2026 (1)
37-46,10
This study was financially supported by the National Natural Science Foundation of China(NSFCNos.81973199 and U23A20514).
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