基于态靶辨治理论探讨结直肠癌辨治思路OA
Discussion on the Differentiation and Treatment of Colorectal Cancer Based on the State-Target Differen‑tiation and Treatment Theory
结直肠癌作为我国发病率第二、死亡率第四的恶性肿瘤,严重威胁国民健康.中医药凭借其增效减毒、预防复发与转移、改善生活质量、延长其生存期等优势,在肠癌综合治疗中具有重要地位.本文基于仝小林院士提出的态靶辨治理论,将结直肠癌发病过程分为湿、瘀、虚三态(三期),确定各阶段相应的调态方与常用靶药,构建结直肠癌的态靶辨治体系,以期能提高结直肠癌的临床疗效.
Colorectal cancer,as the second most common malignant tumor in terms of incidence rate and the fourth in terms of mor‑tality rate in China,poses a serious threat to national health.Traditional Chinese medicine(TCM)plays an important role in the compre‑hensive treatment of colorectal cancer due to its advantages in enhancing efficacy,reducing toxicity,preventing recurrence and metasta‑sis,improving quality of life,and prolonging survival.Based on the theory of state-target differentiation and treatment proposed by aca‑demician Tong Xiaolin,this article divides the pathogenesis of colorectal cancer into three states(three stages):dampness,blood stasis,and deficiency,determines the corresponding state-regulating formulas and commonly used target drugs for each stage,and constructs a state-target differentiation and treatment system for colorectal cancer,with the aim of improving the clinical efficacy of colorectal can‑cer treatment.
李柳;程海波;孙东东;沈卫星;王俊壹;耿雪尘
南京中医药大学第一临床医学院,江苏 南京 210023||南京中医药大学附属医院,江苏 南京 210029||江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023南京中医药大学第一临床医学院,江苏 南京 210023||南京中医药大学附属医院,江苏 南京 210029||江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023南京中医药大学第一临床医学院,江苏 南京 210023||江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023南京中医药大学附属医院,江苏 南京 210029||江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023南京中医药大学第一临床医学院,江苏 南京 210023||江苏省中医药防治肿瘤协同创新中心,江苏 南京 210023
医药卫生
态靶辨治结直肠癌中医药辨治思路仝小林虚态瘀态湿态
state-target differentiation and treatmentcolorectal cancertraditional Chinese medicinedifferentiation and treatment approachTong Xiaolinweak statestagnationwet state
《南京中医药大学学报》 2026 (3)
330-335,6
国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202208)国家中医药管理局高水平中医药重点学科建设项目(国中医药人教函[2023]85号)江苏高校优势学科建设工程资助项目-中医学、中西医结合(PAPD)江苏高校"青蓝工程"资助项目(苏教师函[2023]27号)
评论