基于"从脾论治"理论探讨针刺公孙、太白穴改善下肢肌力的作用机制OA
Exploration of the Mechanism of Acupuncture at Gongsun(SP4)and Taibai(SP3)Acupoints in Improving Lower Limb Muscle Strength Based on the Theory of"Treating from the Spleen"
偏瘫、周围神经病、运动神经元病等疾病患者常伴有下肢活动不利、无力,影响生活质量.现代医学治疗效果欠佳,针灸治疗具有一定优势.临床针刺公孙、太白穴改善下肢肌力效果显著,但相关机制尚未明确.下肢活动不利属于中医"痿证""中风"范畴,文章基于"从脾论治"理论,深入探究针刺公孙、太白穴改善下肢肌力的机制.从中医理论看,两穴位属足太阴脾经,可健脾和胃、促进气血生成,符合"脾主四肢"理论;针刺两穴能触发肢体一过性抽动,促进运动中枢功能恢复、激发经气从而改善下肢肌力,与醒脑开窍针法作用机制类似.其机制可能与以下方面相关:在"脾主四肢"理论下濡养肌肉,改善下肢肌力;脾主升清调控线粒体能量代谢,脾主运化可促进细胞再生与修复以及针刺两穴可改善下肢动脉硬化,调节脂质代谢并抑制炎症反应.多途径协同提升下肢肌肉功能.针刺治疗具有安全、经济、操作简便等优点,有望为下肢肌力减退患者提供有效治疗手段,但目前分子机制尚不明确,需进一步动物实验验证.
Patients with diseases such as hemiplegia,peripheral neuropathy and motor neuron disease often suffer from impaired lower limb mobility and weakness,which significantly affects their quality of life.The therapeutic effects of modern medicine are not very satisfactory,while acupuncture treatment has certain advantages.Clinically,acupuncture at the Gongsun(SP4)and Taibai(SP3)acupoints has shown remarkable effects in improving lower limb muscle strength.However,the relevant mechanisms remain unclear.Lower limb motor dysfunction falls into the category of"flaccidity syndrome""stroke"in traditional Chinese medicine.This article deeply explores the mechanisms by which acupuncture at the Gongsun(SP4)and Taibai(SP3)acupoints improves lower limb muscle strength,based on the theory of"treating from the spleen"in traditional Chinese medicine.According to traditional Chinese medicine theory,these two acupoints belong to the foot Taiyin spleen meridian.They can invigorate the spleen,harmonize the stomach,and promote the generation of Qi and blood,which is in line with the theory that"the spleen governs the four limbs".Acupuncture at these two points can trigger transient limb twitching,promote the recovery of motor central function,and stimulate meridian Qi,thereby improving lower limb muscle strength,which is similar to the mechanism of the Xingnao Kaiqiao acupuncture method.The underlying mechanisms may be related to the following aspects:nourishing muscles under the theory of"spleen governing the limbs",thereby improving lower limb muscle strength;the spleen's function of ascending clear Qi regulating mitochondrial energy metabolism;the spleen's transportation and transformation promoting cell regeneration and repair;and acupuncture at the two points improving lower limb arteriosclerosis,regulating lipid metabolism,and inhibiting inflammatory responses.These multiple pathways work synergistically to enhance lower limb muscle function.Acupuncture treatment has the advantages of safety,economy,and simplicity in operation.It is expected to provide an effective treatment method for patients with decreased lower limb muscle strength.However,the current molecular mechanism is still unclear and requires further verification through animal experiments.
赵月萱;索艳荣;郭仕薪;冯丽莎;孙大伟
天津中医药大学,天津 301617||天津市中医药研究院附属医院,天津 300120赣州市人民医院,江西 赣州 341000中国科学技术出版社,北京 100054天津市中医药研究院附属医院,天津 300120天津中医药大学,天津 301617||天津市中医药研究院附属医院,天津 300120||天津中医药大学第二附属医院,天津 300250
医药卫生
从脾论治公孙穴太白穴下肢肌力理论探讨
treating from the spleenGongsun(SP4)Taibai(SP3)lower limb muscle strengththeoretical discussion
《辽宁中医药大学学报》 2026 (4)
130-134,5
国家自然科学基金地区科学基金项目(82160828)天津市中医药研究院附属医院青年人才助力培养项目-"青苗"计划天津市卫生健康委中医、中西医结合科研课题-重点项目(2023041)河北省中医药管理局中医药类科学研究课题计划项目(T2025053)
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