痉挛型脑瘫头颅磁共振成像分类系统分型与运动功能发育水平的相关性OA

Objective To explore the correlation between magnetic resonance imaging(MRI)findings and motor function development level in children with spastic cerebral palsy(SCP)based on the magnetic resonance imaging classification system(MRICS).Methods Clinical data of 122 children with SCP were retrospectively collected,including cranial MRI classification results based on MRICS and assessment data from the gross motor function classification system(GMFCS),gross motor function measure(GMFM),manual ability classification system(MACS),and the Peabody developmental motor scales,2nd edition(PDMS-2).Multiple linear regression model was used to analyze the association between MRI classification under MRICS and motor function development level.Results Abnormal cranial MRI findings were observed in 85.25%of the children with SCP,with white matter injury-dominant type being the most common(40.16%).The proportions of children with low birth weight,premature birth,and a history of birth asphyxia were higher in this type.MRI classification under MRICS was correlated with GMFM scores in children with SCP,but showed no significant correlation with PDMS-2 scores.The GMFM scores of children with mixed-type SCP were significantly lower than those of children with other types(P<0.05).In the sitting and crawling-kneeling functional domains,the GMFM scores of children with the white matter injury-dominant type and normal MRI type were significantly higher than those of children with other types(P<0.05).Conclusion Most children with SCP have abnormal cranial MRI findings,and the pattern of brain injury is associated with low birth weight,premature birth,and a history of birth asphyxia.Among the cranial MRI classifications based on MRICS,children with mixed-type SCP have the most severe gross motor dysfunction,while those with white matter injury-dominant type and normal MRI type have a better prognosis of gross motor function.