穿破石的本草考证OA

Literary Research on the Herbal Origin of Radix Cudraniae

中文摘要英文摘要

本文通过系统查阅历代本草、方书及地方药物志,并结合近现代资料,对穿破石的名称、基原、学名考订、产区、采收加工及炮制、入药部位、性味功效进行了全面考证.结果表明"穿破石"之名首见于《岭南采药录》,后被现代标准采用.其基原可追溯至《诗经》,自唐以来主流基原为桑科植物构棘Maclura cochinchinensis或柘Maclura tricuspidata,与 1977 年版《中国药典》基原一致.该药原产地可追溯至江南,现代多分布于我国东部至西南各省区.采集加工方面,全年可采,洗净切片晒干;古代常用酒煎、浸酒等法炮制,现代则多以干燥根切片入药.其性味历经演变,从唐代甘温至清代甘平,现代认定为凉、淡、微苦,归经主入肝经;功效主要包括活血祛瘀、舒筋活络、清热利湿.临床应用从晋代补虚损,渐扩展至唐代清心火、明清治疮疡跌打,现代更用于治疗急性和慢性肝炎、肺结核等.本研究厘清了穿破石的药用历史与基原变迁,为其规范应用与深入研究提供文献依据.

In this paper,a comprehensive textual research was conducted on the nomenclature,original plant,scientific name identification,producing areas,collection,processing and preparation,medicinal parts,as well as properties and efficacies of Radix Cudraniae by systematically reviewing herbal works,formularies and local pharmaceutical records of successive dynasties,combined with modern and contemporary literatures.The results showed that the name"Radix Cudraniae"first appeared in Lingnan Caiyao Lu,and was later adopted by modern pharmaceutical standards.Its original plant can be traced back to The Book of Songs.Since the Tang Dynasty,the mainstream original plants have been Maclura cochinchinensis or M.tricuspidata,which is consist-ent with the sourcespecified in the 1977 edition of Pharmacopeia of the People's Republic of China.The original producing area of this herb can be traced to the Jiangnan region,and modern distribution is mainly in provinces and regions from eastern to southwestern China.In terms of collection and processing,the herb can be collected all year round,washed,sliced and dried in the sun.In ancient times,it was commonly prepared by decocting with wine or macerating in wine,while in modern times,the dried root slices are mostly used as medicinal mate-rial.Its medicinal properties have undergone evolution:from sweet and warm in the Tang Dynasty to sweet and neutral in the Qing Dynasty,and it is currently recognized as cool,bland and slightly bitter,mainly attributive to the Liver Meridian.Its main efficacies include activating blood circulation to resolve stasis,relaxing sinews and activating collaterals,clearing heat and draining dampness.In clinical application,it was originally used for tonifying deficiency in the Jin Dynasty,then gradually extended to clearing heart-fire in the Tang Dynasty,trea-ting sores and injuries in the Ming and Qing dynasties,and is now applied to diseases such as acute and chronic hepatitis and pulmonary tuberculosis.This study clarifies the medicinal history and original plant changes of Ra-dix Cudraniae,and provides literature evidence for its standardized application and in-depth research.

干秋玲;刘顶鼎;薛兰琼;曾贵荣;陈唯实;吴远华;吴雪梅

贵州中医药大学 药学院,贵州 贵阳 550025贵州中医药大学 药学院,贵州 贵阳 550025贵州中医药大学 药学院,贵州 贵阳 550025湖南省药物安全评价研究中心,湖南 长沙 410331贵州中医药大学 药学院,贵州 贵阳 550025贵州中医药大学第一附属医院 神经内科 贵州 贵阳 550002贵州中医药大学第一附属医院 康复科 贵州 贵阳 550002

医药卫生

穿破石基原性味功效

Radix Cudraniaeoriginal plantmedicinal propertiesefficacies

《贵州中医药大学学报》 2026 (2)

67-73,7

1.国家自然科学基金项目(82160894)2.贵州中医药大学研究生教育创新计划项目(YCXKYS2025040)3.贵州中医药大学研究生教育创新计划项目(YCXKYS2023018).

10.16588/j.cnki.issn2096-8426.2026.02.012

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