Periodontitis-associated salivary microbiota exacerbates systemic osteoclastogenesis via gut modulation and tryptophan metabolism suppression in ovariectomized miceOA

作者：Nannan Wang;Fuhua Yan;Jun Qian;Min Wang;Lili Li;Wenzheng Liao;Rixin Chen;Hua Nie;Ruiyang Ge;Fangfang Sun

作者单位：Nanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaShenzhen Hospital,Southern Medical University,Shenzhen,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,ChinaNanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University,Nanjing,China

刊名：《国际口腔科学杂志（英文版）》 2026 (1)

页码/页数：152-164,13

基金：Financial support was provided by the National Natural Sciences Foundation of China(82270979),High-Level Hospital Construction Project(0224C001,0224C050),and Cultivation Program for Reserve Talents for Academic Leaders(2023A208)of Nanjing Stomatological Hospital,Affiliated Hospital of Medical School,Institute of Stomatology,Nanjing University.The authors also thank BioRender for providing drawing elements.

DOI：10.1038/s41368-025-00415-2