首页|期刊导航|国际口腔科学杂志(英文版)|Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells

Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cellsOA

Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells

Haoran Du;Jianguang Xu;Jingsong Wang;Hideaki Kagami;Xianqi Li;Su Chen;Jian Zhou;Qiong Li;Chenchen Zhou;Junji Xu;Kang Gao;Zixiao Li;Yifan Xu;Ousheng Liu;Bing Li

Department of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China||Beijing Laboratory of Oral Health,Capital Medical University,Beijing,ChinaCollege & Hospital of Stomatology,Key Laboratory of Oral Diseases Research of Anhui Province,Anhui Medical University,Hefei,Anhui,ChinaBeijing Laboratory of Oral Health,Capital Medical University,Beijing,ChinaDepartment of Dentistry and Oral and Surgery,Aichi Medical University,Nagakute,Aichi,JapanDepartment of Oral and Maxillofacial Surgery,School of Dentistry,Matsumoto Dental University,Shiojiri,JapanDepartment of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,ChinaDepartment of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China||Beijing Laboratory of Oral Health,Capital Medical University,Beijing,China||Laboratory for Clinical Medicine,Capital Medical University,Beijing,China||Laboratory for Oral and General Health Integration and Translation,Beijing Tian tan Hospital,Capital Medical University,Beijing,ChinaBeijing Laboratory of Oral Health,Capital Medical University,Beijing,China||Laboratory of Tissue Regeneration and Immunology and Department of Periodontics,Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction,School of Stomatology,Capital Medical University,Beijing,China||Laboratory for Clinical Medicine,Capital Medical University,Beijing,ChinaState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Diseases & Department of Pediatric Dentistry,West China Hospital of Stomatology,Sichuan University,Chengdu,Sichuan,ChinaCollege of Stomatology,Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences,Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education,Chongqing Medical University,Chongqing,ChinaDepartment of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China||Beijing Laboratory of Oral Health,Capital Medical University,Beijing,ChinaDepartment of International Medical Center,Beijing Stomatological Hospital,Capital Medical University,Beijing,China||Beijing Laboratory of Oral Health,Capital Medical University,Beijing,ChinaBeijing Laboratory of Oral Health,Capital Medical University,Beijing,China||Laboratory for Clinical Medicine,Capital Medical University,Beijing,ChinaXiangya Stomatological Hospital,Central South University,Changsha,Hunan,ChinaSchool and Hospital of Stomatology,Shanxi Medical University,Taiyuan,Shanxi,China

《国际口腔科学杂志(英文版)》 2026 (1)

137-151,15

This work was supported by the National Natural Science Foundation of China(82170951,82470961)the Beijing Natural Science Foundation(7222079)the Beijing Hospital Authority"Dengfeng"Talent Training Plan(DFL 20221301)the Beijing Stomatological Hospital,Capital Medical University Young Scientist Program(No.YSP202401).The authors gratefully acknowledge the Laboratory for Clinical Medicine and the Central Laboratory of Capital Medical University for their technical support and funding.We also thank the Japan China Sasakawa Medical Fellowship for their generous support and funding.

10.1038/s41368-025-00406-3

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