高危儿脑瘫风险和运动-认知-语言发育的特征分析及相关性研究OA

Objective To investigate the characteristics of cerebral palsy(CP)risk and early motor,cognitive,and language development in high-risk infants,as well as their correlations,in order to provide scientific evidence for early targeted intervention.Methods High-risk infants with corrected ages ranging from 3 to 24 months were assessed using the Hammersmith Infant Neurological Examination(HINE)to evaluate CP risk and the Bayley Scales of Infant and Toddler Development,Third Edition(Bayley-Ⅲ),to assess motor,cognitive,and language development.Differences and correlations among groups stratified by CP risk level and the number of delayed developmental domains were analyzed.Results A total of 632 high-risk infants were included.The proportions of infants categorized as low CP risk,requiring continued monitoring,high CP risk,and severe CP risk were 23.58％,33.86％,36.07％,and 6.49％,respectively.The prevalence rates of developmental delay were 54.75％for gross motor function,36.71％for fine motor function,40.19％for cognition,40.03％for receptive language,and 22.78％for expressive language.Higher CP risk levels or a greater number of delayed developmental domains were associated with lower developmental scores across all functional ar-eas(P＜0.001).HINE scores showed significant positive correlations with motor,cognitive,and language outcomes(P＜0.001),and significant positive correlations were also observed among different developmental domains(P＜0.001).Conclusion High-risk infants may exhibit neurodevelopmental delays at an early stage,and the severity of de-lay is closely associated with both the level of CP risk and the number of affected developmental domains.Interactions a-mong motor,cognitive,and language functions are evident.These findings underscore the importance of early comprehen-sive assessment and proactive rehabilitation intervention in high-risk infants.