多不饱和脂肪酸对奶牛免疫功能的影响及其机制研究进展OA
Research Progress on Effects of Polyunsaturated Fatty Acids on Immune Function of Dairy Cows and Its Mechanism
多不饱和脂肪酸(PUFAs)参与奶牛机体脂质代谢、生物膜磷脂构成、繁殖、免疫功能及生物活性物质合成等重要生理过程.在集约化养殖中,增强奶牛的免疫功能对抵抗病原体和提高产品质量非常重要,越来越多的研究表明,PUFAs在调节奶牛免疫功能中发挥着关键作用.本文对饲粮中补充 PUFAs 调节奶牛免疫功能的最新研究进行综述,主要讨论了 n-3 和 n-6 PUFAs对奶牛免疫功能和生产性能的影响、饲粮中n-3 与n-6 PUFAs的平衡以及PUFAs的分子作用机制,旨在加深理解PUFAs对免疫系统的营养作用,制定增强奶牛免疫功能的营养方案,为提高奶牛健康水平和生产性能提供理论依据.
Polyunsaturated fatty acids(PUFAs)are involved in key physiological processes of dairy cows,such as lipid metabolism,phospholipid composition of biological membranes,reproduction,immune function and synthesis of bioactive substances.In intensive farming,enhancing the immune function of dairy cows is im-portant for fighting off pathogens and boosting products quality.More and more studies have shown that PUFAs play a key role in regulating the immune function of dairy cows.In this paper,the effects of PUFAs supple-mentation in diets on the regulation of dairy cows'immune function in the latest researches are reviewed.We focus on the effects of n-3 and n-6 PUFAs on immune function and performance of dairy cows,balance of n-3 and n-6 PUFAs in the diets,and the molecular mechanisms of PUFAs.The aim is to deepen the understand-ing of the nutritional roles of PUFAs in the immune system,to come up with nutritional strategies that boost the immune function of dairy cows,and to provide a solid foundation for improving health and performance of dairy cows.[Chinese Journal of Animal Nutrition,2026,38(3):1602-1611]
吕佳颖;崔占鸿;刘书杰;李国彰
青海大学畜牧兽医科学院,青海省牦牛工程技术研究中心,青海省高原放牧家畜动物营养与饲料科学重点实验室,农业农村部青藏高原放牧牦牛藏羊动物营养与饲草料重点实验室,西宁 810016青海大学畜牧兽医科学院,青海省牦牛工程技术研究中心,青海省高原放牧家畜动物营养与饲料科学重点实验室,农业农村部青藏高原放牧牦牛藏羊动物营养与饲草料重点实验室,西宁 810016青海大学畜牧兽医科学院,青海省牦牛工程技术研究中心,青海省高原放牧家畜动物营养与饲料科学重点实验室,农业农村部青藏高原放牧牦牛藏羊动物营养与饲草料重点实验室,西宁 810016青海大学生态环境工程学院,农业农村部高原冷水鱼养殖与生态环境保护重点实验室(部省共建),西宁 810016
农业科技
多不饱和脂肪酸奶牛免疫功能生产性能
polyunsaturated fatty acidsdairy cowsimmune functionperformance
《动物营养学报》 2026 (3)
1602-1611,10
农业农村部青藏高原放牧牦牛藏羊动物营养与饲草料重点实验室开放基金(2025-YYKF-04)
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