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基于"清浊相干"理论探讨大肠癌病机与治则OA

Discussion on the pathogenesis and treatment of colorectal cancer based on the theory of"interference between clear and turbid"

中文摘要英文摘要

大肠癌指发生在结直肠的恶性肿瘤,中医属"肠风""脏毒"等范畴.清浊是人体中同时存在、相互对立的一对物质体系,生理状态下清与浊各安其位,互不干扰.清浊相干是大肠癌发病的基本病机.清浊相干包括清浊逆作、清浊失间、清不消浊等"清"与"浊"失于常道、相互干扰的发病机制.本文提出分清消浊治法,通过分化清浊、消泄浊毒,使清浊恢复本位,正能抗邪,癌毒能消,以期为大肠癌的中医临床诊疗提供有益思路.

Colorectal cancer refers to malignant tumour occurring in the colorectum,which belongs to the category of changfeng(intestinal wind)and zangdu(toxicity of internal organs)in Traditional Chinese Medicine(TCM).Clear and turbid are a pair of opposing material systems that coexist in the human body,and in physiological state,they have their own positions and do not interfere with each other.The confusion of the clear and the turbid with each other is a basic pathogenesis in the development of colorectal cancer.The confusion of the clear and the turbid with each other includes the pathogenesis of clear and turbid being out of the normal way and interfering with each other,such as adverse action of clear and turbid,loss of distinction between clear and turbid,and the clear failing to disperse the turbid.This paper proposes the method of separating the clear and dissipating the turbid,which can restore clear and turbid to its original position through differentiating clear and turbid and eliminating turbid toxins,so that the healthy qi can fight against the evil,and the cancerous toxin can be eliminated,which is expected to provide useful ideas for the TCM diagnosis and treatment of colorectal cancer.

王金滟;刘传波;相伟;张彤;梁秋然;李姝

北京中医药大学第二临床医学院 北京 100078北京中医药大学东方医院新乐市中医医院肿瘤科中国中医科学院西苑医院北京中医药大学第二临床医学院 北京 100078北京中医药大学第二临床医学院 北京 100078

医药卫生

结直肠癌清浊相干癌毒病机治则

colorectal cancerinterference between clear and turbidcancer toxinpathogenesisprinciple of treatment

《现代中医临床》 2026 (2)

39-43,5

国家自然科学基金面上项目(No.82174461)北京中医药"十四五"重点专科规划项目(No.BJZKBC0003)

10.3969/j.issn.2095-6606.2026.02.008

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