胃食管反流病中医药研究现状、难点及辨治策略OA
Current Research Status,Challenges,Differentiation and Treatment Strategies of Traditional Chinese Medicine for Gastroesophageal Reflux Disease
系统梳理胃食管反流病(GERD)的中医药研究现状与诊疗策略.发现中医药通过病证结合模式,在改善各型GERD症状、促进黏膜修复、调节情志及协同减停西药方面体现多靶点优势.针对症状重叠、疗效局限等临床难点,提出GERD异病同治、脏腑相关整合调节等策略.未来需深化复方机制研究,推动符合中医药理论、人用经验和临床试验相结合的审评证据体系的"三结合"审评体系的中药研发,优化中西医结合诊疗模式,以提升GERD防治水平.
This article systematically reviews the current research status as well as diagnosis and treatment strategies of traditional Chinese medicine(TCM)for gastroesophageal reflux disease(GERD).Studies demonstrate that TCM,based on the"disease-syndrome combination"approach,exhibits multi-target advantages in alleviating symptoms of various GERD subtypes,promoting mucosal repair,regulating emotions,and facilitating the reduction of western medication.To address clinical challenges such as symptom overlap and limited therapeutic efficacy,strategies have been proposed including"treating different diseases with the same method"and integrated regulation based on viscera correlation.Future efforts should focus on elucidating the mechanisms of compound prescriptions,promoting TCM drug development under the"three-combination"evaluation framework that integrates TCM theory,human experience and clinical trial evidence,and optimizing integrated traditional and western medicine models to enhance GERD management.
王凤云;汪洋;黄开月;许璐司;唐旭东;吕咪;周秉舵;张北华;王轶;徐亭亭;何聪;王小康;刘鑫
中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091北京中医药大学中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091中国中医科学院西苑医院脾胃病研究所中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091上海中医药大学附属岳阳中西医结合医院中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091上海中医药大学附属岳阳中西医结合医院上海中医药大学附属岳阳中西医结合医院上海中医药大学附属岳阳中西医结合医院中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091北京中医药大学
胃食管反流病中医药疗法中西医结合疗法病证结合
gastroesophageal reflux diseasetraditional Chinese medicine therapyintegrated traditional Chinese and western medicine therapydisease-syndrome combination
《中医杂志》 2026 (4)
392-396,5
国家自然科学基金(82374434,82174363)重大疑难疾病中西医临床协作项目(ZDYN-2024-A-071)中国科学技术协会2024年中医脾胃病学学科发展研究(2024XKFZYJ)国家中医药管理局高水平中医药重点学科建设项目(zyyzdxk-2023219)中国中医科学院科技创新工程(CI2021A01001)
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