2025年中医诊断学研究进展OA

In 2025,guided by national policies and profoundly empowered by artificial intelligence technologies,the field of traditional Chinese medicine(TCM)diagnostics has advanced across five key dimensions:theoretical innovation,technological transformation,basic research,clinical application,and educational pedagogy.Large model technologies have transitioned from concept validation to clinical application,achieving breakthroughs in lightweight ancient text models and multimodal diagnostic assistance systems.Research on diagnostic theory has focused on the revitalization of classics,encompassing ancient text mining of tongue and pulse diagnostics,as well as hand diagnosis,abdominal diagnosis,and ethnic medicine diagnostic methods.Syndrome research has deepened the refinement and standardization of pattern differentiation,with the gradual promotion of"data-knowledge"dual-driven pattern differentiation methods.Animal models combining disease and syndrome,such as Cold pattern,Heat pattern,Phlegm-Blood stasis pattern,and Damp-Heat pattern,have become increasingly stable.Metabolomics and microbiomics have revealed more biomarkers and signaling pathways associated with TCM syndromes.Diagnostic equipment has achieved multimodal data fusion and upgrades,with significant improvements in the clinical adaptability of flexible sensor pulse-taking devices,intelligent tongue diagnostic systems,and infrared thermal imaging equipment.Wearable devices are expanding applications in health management scenarios.Educational reform,through digital platforms,scenario simulation,and ideological-political integration,has constructed a"theory-practice-thinking"trinity training system,overcoming traditional teaching bottlenecks.Simultaneously,the discipline's development still faces challenges such as insufficient interpretability of large models,inadequate depth in multi-diagnostic method data fusion,and the need to enhance the specificity of syndrome biomarkers.This article systematically reviews the core research achievements in TCM diagnostics in 2025,aiming to provide a reference for the discipline's development.