基于属性层次模型评价那屈肝素钙的临床使用合理性OA

AIM To establish the drug use evaluation(DUE)criteria of nadroparin calcium,and evaluate its ratonality of clinical application,providing a reference for rational clinical use.METHODS A rational drug use evaluation team was set up to establish the DUE criteria of nadroparin calcium based on the evidence-based medical/pharmacy evidence.The attribute hierarchical model(AHM)method was used to evaluate the rationality of clinical use of nadroparin calcium.RESULTS During the perioperative period,there were many unreasonable prophylactic uses of nadroparin calcium in the medical records of this evaluation,with the rational rate of use being higher in the internal medicine department compared to surgical department.The primary issues with the unreasonable clinical use of nadroparin calcium were improper use and dosage(281 cases,82.40％),lack of laboratory monitoring(178 cases,52.20％),and inappropriate timing of medication administration(156 cases,45.75％).The medical record score(MRS)was(73.16±9.91)points,with cases rated as qualified and good accounting for 57.77％and 34.90％,respectively.CONCLUSION The DUE criteria of nadroparin calcium established are scientific and feasible to evaluate the rationality of nadroparin calcium for clinical use.There are certain concerns regarding the clinical use of nadroparin calcium in the hospital.The evaluation grades for medical records concerning nadroparin calcium are mostly categorized as qualified or good,with very few cases rated as excellent or unqualified.Clinicians need to pay attention to the unreasonable use of nadroparin calcium.