磁共振多b值DWI联合IFIR-MRA对移植肾急性排斥反应的早期诊断价值OA
The early diagnostic value of magnetic resonance multi-b-value DWI combined with IFIR-MRA for acute rejection of transplanted kidneys
目的:探讨磁共振多b值扩散加权成像(DWI)联合流入反转恢复磁共振血管成像(IFIR-MRA)对移植肾急性排斥反应(AR)的早期诊断价值.方法:选取2021年5月—2024 年12月本院收治的肾移植患者 82例为研究对象,所有患者均接受病理学检查、磁共振多b值DWI检查及IFIR-MRA检查.根据病理学检查结果分为AR组(n=57)和非AR组(n=25),以病理学检查结果为金标准,比较磁共振多b值DWI检查、IFIR-MRA检查及联合诊断与金标准的一致性,比较不同方法诊断移植肾AR的效能.结果:磁共振多b值DWI检查诊断移植肾AR的敏感度为 82.46％(47/57),特异度为 68.00％(17/25),准确度为78.05％(64/82),Kappa值为 0.493.IFIR-MRA检查诊断移植肾AR的敏感度为 78.95％(45/57),特异度为 64.00％(16/25),准确度为74.39％(61/82),Kappa值为0.455.磁共振多b值DWI联合IFIR-MRA诊断移植肾AR的敏感度为 98.25％(56/57),特异度为96.00％(24/25),准确度为97.56％(80/82),Kappa值为0.942.磁共振多b值DWI联合IFIR-MRA诊断移植肾AR的敏感度、特异度、准确度高于单一诊断方法(P<0.05).结论:磁共振多b值DWI联合IFIR-MRA诊断移植肾AR具有较高的效能,值得在临床上推广应用.
Objective:To explore the early diagnostic value of magnetic resonance multi-b-value diffusion-weighted imaging(DWI)combined with inflow reversal recovery magnetic resonance angiography(IFIR-MRA)for acute rejection(AR)following kidney transplantation.Methods:A total of 82 patients who underwent kidney transplantation and were admitted to our hospital from May 2021 to December 2024 were enrolled as the research subjects.All patients underwent pathological examination,magnetic resonance multi-b-value DWI examination and IFIR-MRA examination.According to the results of pathological examination,the patients were divided into the AR group(n=57)and the non-AR group(n=25).Taking pathological examination as the gold standard,the consistency of magnetic resonance multi-b-value DWI examination,IFIR-MRA examination,combined diagnosis and the gold standard was compared,and the efficacy of different methods in diagnosing AR following kidney transplantation was compared.Results:The sensitivity of magnetic resonance multi-b-value DWI examination in diagnosing AR in kidney transplantation was 82.46％(47/57),the specificity was 68.00％(17/25),the accuracy was 78.05％(64/82),and the Kappa value was 0.493.The sensitivity of IFIR-MRA examination in diagnosing AR in kidney transplantation was 78.95％(45/57),the specificity was 64.00％(16/25),the accuracy was 74.39％(61/82),and the Kappa value was 0.455.The sensitivity of magnetic resonance multi-b-value DWI combined with IFIR-MRA in diagnosing AR in kidney transplantation was 98.25％(56/57),the specificity was 96.00％(24/25),the accuracy was 97.56％(80/82),and the Kappa value was 0.942.The sensitivity,specificity and accuracy of magnetic resonance multi-b-value DWI combined with IFIR-MRA in diagnosing AR in kidney transplantation were higher than those of the single diagnostic method(P<0.05).Conclusion:Magnetic resonance multi-b-value DWI combined with IFIR-MRA has a high diagnostic efficacy in the diagnosis of renal transplantation AR and is worthy of wide clinical application.
张思微;吴仪仪;王佳丽
徐州医科大学附属医院医学影像科,江苏 徐州 221002徐州医科大学附属医院医学影像科,江苏 徐州 221002徐州医科大学附属医院医学影像科,江苏 徐州 221002
医药卫生
肾移植磁共振成像磁共振血管造影术
Kidney TransplantationMagnetic Resonance ImagingMagnetic Resonance Angiography
《中国临床医学影像杂志》 2026 (3)
191-195,5
徐州市科技项目(KC23279).
评论