Pan-prediction of major histocompatibility complex class Ⅱ-restricted epitopes across species via an AlphaFold-based quantification schemeOA
Pan-prediction of major histocompatibility complex class Ⅱ-restricted epitopes across species via an AlphaFold-based quantification scheme
Suqiu Wang;Lifeng Zhang;Sheng Wang;Shi Xu;Hanchun Yang;Nianzhi Zhang;Lingming Kong;Dongmei Hu;Liangzhen Zheng;Caiyi Fei;Liubao Du;Ziche Tang;Malgorzata A.Garstka;Onur Serçinoğlu
State Key Laboratory of Veterinary Public Health and Safety,Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs,College of Veterinary Medicine,China Agricultural University,Beijing,China||Animal Quarantine Institute,Science and Technology Research Center of China Customs,Beijing,ChinaDepartment of Resources,Science and Technology Research Center of China Customs,Beijing,ChinaShanghai Zelixir Biotech Company Ltd.,Shanghai,China||CAS Key Laboratory of Quantitative Engineering Biology,Shenzhen Institute of Synthetic Biology,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Guangdong,ChinaNanjing Chengshi Biomedical Technology(TheraRNA)Co.,Ltd.,Jiangsu,ChinaState Key Laboratory of Veterinary Public Health and Safety,Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs,College of Veterinary Medicine,China Agricultural University,Beijing,ChinaState Key Laboratory of Veterinary Public Health and Safety,Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs,College of Veterinary Medicine,China Agricultural University,Beijing,ChinaNanjing Chengshi Biomedical Technology(TheraRNA)Co.,Ltd.,Jiangsu,ChinaState Key Laboratory of Veterinary Public Health and Safety,Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs,College of Veterinary Medicine,China Agricultural University,Beijing,ChinaShenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Guangdong,China||Shanghai Zelixir Biotech Company Ltd.,Shanghai,ChinaNanjing Chengshi Biomedical Technology(TheraRNA)Co.,Ltd.,Jiangsu,ChinaState Key Laboratory of Veterinary Public Health and Safety,Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs,College of Veterinary Medicine,China Agricultural University,Beijing,ChinaState Key Laboratory of Veterinary Public Health and Safety,Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs,College of Veterinary Medicine,China Agricultural University,Beijing,ChinaDepartment of Endocrinology,The Second Affiliated Hospital of Xi'an Jiaotong University,Shaanxi,China||Core Research Laboratory,The Second Affiliated Hospital of Xi'an Jiaotong University,Shaanxi,ChinaDepartment of Bioengineering,Faculty of Engineering,Gebze Technical University,Kocaeli,Türkiye
major histocompatibility complex class Ⅱ(MHC-Ⅱ)-restricted epitopeAlphaFold-prediction(AF-pred)vaccine designpan-predicting
major histocompatibility complex class Ⅱ(MHC-Ⅱ)-restricted epitopeAlphaFold-prediction(AF-pred)vaccine designpan-predicting
《微生物与宿主健康（英文）》 2026 (3)
186-204,19
This study was supported by the National Key Research and Development Program of China(grant number 2021YFD1800100 to N.Z.),the National Natural Science Foun-dation of China(grant number 32172871 to N.Z.),the 2115 Talent Development Program of China Agricultural University to N.Z.This study was supported by High-performance Computing Platform of China Agricultural University.
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