86例犬库兴综合征的病例回顾性分析OA
Retrospective analysis of 86 cases of canine Cushing's syndrome
旨在回顾性分析2024 年6 月至 2025 年 3 月在中国农业大学动物医院就诊的 86 例犬库兴综合征.结果显示,该病诊断的中位年龄为 10.8岁,迷你贵宾犬占比高达59.3%,雌雄患病比为1.7∶1;66.7%(48/72)的患犬经促肾上腺皮质激素刺激试验确诊,仅有 27.8%(20/72)的患犬经低剂量地塞米松抑制试验确诊;83.7%的患犬未准确区分肾上腺皮质功能亢进类型;肾上腺皮质功能亢进患犬肾上腺超声形态多呈双侧或单侧增大,肝脏超声呈类固醇性肝病与胆汁淤积;曲洛斯坦治疗的剂量为 2.16 mg/(kg·d),四分位数间距(IQR):1.45～2.85 mg/(kg·d),能有效控制高皮质醇血症.本分析结果为临床兽医师提供了诊疗参考.
A retrospective study was conducted on 86 canine hyperadrenocorticism(HAC)cases diagnosed at the China Agricultural Uni-versity Veterinary Teaching Hospital from 2024 to 2025.The median age of the infected dogs at diagnosis was 10.75 years,with Miniature Poodles accounting for 59.3%of the cases.The female-to-male ratio was 1.7∶1.The diagnosis was confirmed by adrenocorticotropic hor-mone(ACTH)stimulation test in66.7%of the cases,and the low-dose dexamethasone suppression test in 27.8%of the cases.Notably,83.7%of the cases could not be accurately classified into HAC subtypes.The ultrasonographic findings revealed bilateral or unilateral adrenal enlargement in most HAC-affected dogs,with hepatic changes consistent with steroid hepatopathy and cholestasis.Trilostane therapy(median dosage:2.16 mg/(kg·d),IQR:1.45-2.85 mg/(kg·d))effectively controlled hypercortisolism in the studied population.The present analysis may serve as reference for veterinarians in clinical practice
陈鸿;刘雨馨;邓娴;冯芷珊;吴定洲;周雪影;韩博
中国农业大学动物医学院,北京 100193中国农业大学动物医学院,北京 100193中国农业大学动物医学院,北京 100193中国农业大学动物医学院,北京 100193中国农业大学动物医学院,北京 100193中国农业大学动物医学院,北京 100193中国农业大学动物医学院,北京 100193
农业科技
犬库兴综合征曲洛斯坦回顾性分析
canineCushing's syndrometrilostaneretrospective analysis
《畜牧与兽医》 2026 (4)
122-129,8
中国农业大学2115人才工程项目
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