基于中医体质理论探讨脑出血的精准预防OA
Precision Prevention of Intracerebral Hemorrhage Based on Traditional Chinese Medicine Constitution Theory
脑出血(intracerebral hemorrhage,ICH)致死致残率高,临床预防存在精准性、个性化不足问题.中医体质理论源于"治未病",与精准医学理念契合,且与 ICH 发病风险密切相关,其"内外风"交互机制为 ICH 精准预防奠定理论基础.该理论下的精准预防策略包括:以体质辨识筛查高危人群、构建含体质因素的风险预测模型、结合体质与气象因素开展个性化预警、针对高危体质实施源头干预.当前研究面临体质分类客观化不足、机制研究不深、临床转化滞后等挑战,未来需推进体质辨识标准化、深化机制研究、加强临床转化并构建中西医结合预防体系.中医体质理论为 ICH 精准预防提供了独特框架,深入研究将助力实现"未病先防、既病防变"目标,减轻疾病负担.
Intracerebral Hemorrhage(ICH)features high mortality and disability rates,and clinical prevention is plagued by insufficient precision and individualization.Rooted in the concept of preventive treatment of disease,the Theory of Constitution in Traditional Chinese Medicine(TCM)aligns with the notion of treatment tailored to the individual in preci-sion medicine and has been proven closely associated with ICH risk.Its mechanism of interaction between internal and ex-ternal"wind"lays a theoretical foundation for the precise prevention of ICH.Precision prevention strategies based on this theory include screening high-risk groups through constitution identification,developing risk prediction models incorporating constitutional factors,implementing personalized early warning and protection by combining constitution with meteorological factors,and conducting source interventions targeting high-risk constitutions.Current research faces challenges such as inad-equate objectification of constitutional classification,superficial mechanistic studies,and delayed clinical translation.Future efforts should focus on advancing the standardization of constitution identification,deepening mechanistic research,strength-ening clinical translation,and establishing an integrated TCM-Western medicine prevention system.The TCM Constitution Theory provides a unique framework for the precise prevention of ICH,and in-depth research will help achieve the goals of preventing disease before its onset and halting its progression after onset,thereby reducing the disease burden of ICH.
范小璇;李翠娟;马思田;司泽钰;封玉宁;齐菲
陕西中医药大学,陕西 咸阳 712046||陕西中医药大学附属医院,陕西 咸阳 712000||陕西省中医脑病医学研究中心,陕西 咸阳 712000陕西中医药大学,陕西 咸阳 712046西安市中医医院,陕西 西安 710021北京空港医院,北京 101300乐山市中医医院,四川 乐山 614000陕西中医药大学附属医院,陕西 咸阳 712000
医药卫生
脑出血中医体质精准预防
intracerebral hemorrhagetraditional chinese medicine constitutionprecision prevention
《现代中医药》 2026 (2)
43-48,6
国家中医药管理局高水平重点学科建设项目(国中医药人教函[2022]226号)全省"双链融合"中青年科研创新团队(2022-SLRH-LJ-015)陕西省中医脑病临床医学研究中心建设项目(陕科社发[2017]176号)
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