荨麻多糖对断奶仔猪生长性能、血液生化指标及抗氧化功能的影响OA

To investigate the effects of nettle(Urtica cannabina L.,UPL)on growth performance,blood bio-chemical indices,and antioxidant function in weaned piglets,60 Duroc×Landrace×Yorkshire crossbred piglets(half male and half female)weaned at 21 days of age were randomly divided into 3 groups.Group A was fed a basal diet,while groups B and C received basal diets supplemented with 150 mg/kg and 300 mg/kg UPL,respectively.The trial included a 3-day adaptation period and a 42-day experimental period.The results showed:① compared with group A,groups B and C exhibited significantly higher average daily feed intake(P<0.05)and sig-nificantly lower diarrhea index(P<0.05).Group C showed significantly increased final body weight and average daily gain(P<0.05),along with sig-nificantly reduced feed-to-gain ratio(P<0.05).② Compared with group A,group C demonstrated significantly elevated serum levels of growth hormone and insulin-like growth factor-1,and significantly reduced somatostatin levels(P<0.05).③ Group C displayed significantly improved antioxidant function compared to group A(P<0.05).④ Groups B and C showed sig-nificantly lower serum D-lactate concentration and diamine oxidase activity(P<0.05),and significantly higher alkaline phosphatase activity(P<0.05)than group A.Group C also exhibited significantly reduced serum myeloperoxidase,alanine aminotransferase and aspartate aminotransferase activities(P<0.05).⑤Compared with group A,group C had significantly lower serum tumor necrosis factor-α and interleukin-6 levels(P<0.05),and significantly higher transforming growth factor-β and interleukin-10 levels(P<0.05).⑥ Groups B and C showed significantly increased abundance of Lactobacillus and Bifidobacterium in feces compared to group A(P<0.05).In conclusion,dietary supplementation with 300 mg/kg UPL significantly improved growth performance and antioxidant function in weaned piglets.