黄柏提取物对断奶仔猪生长性能、肠道发育及抗氧化功能的影响OA

This study aimed to investigate the effects of Phellodendron extract(PE)on growth performance,intestinal development and antioxidant function in weaned piglets.A total of forty-eight healthy 21-day-old crossbred weaned piglets(Duroc×Landrace×Yorkshire,male∶female=1∶1)were randomly assigned to control group and experimental group with six replicates per group and four piglets per replicate.Piglets in the control group were fed a basal diet,and piglet in experimental group were fed the basal diet supplemented with 120 mg/kg PE.The pre-trial period was 3 d,and the formal trial period was 21 d.The results showed that,compared with con-trol group,piglets in experimental group had sig-nificantly increased final body weight(FBW)and average daily gain(ADG)(P<0.05),while feed-to-gain ratio(F/G)and diarrhea index(DI)were sig-nificantly decreased(P<0.05).The intestinal villus height-to-crypt depth ratio(V/C)was significantly increased(P<0.05),whereas the activities of diamine oxidase(DAO),regenerating islet-derived protein 3(REG-3)and myeloperoxidase(MPO)in intes-tinal tissues were significantly reduced(P<0.05).In addition,the relative protein expression levels of insulin-like growth factor 1(IGF-1)and glucagon-like peptide 2(GLP-2)in the duodenum and jejunum were significantly increased(P<0.05).Furthermore,piglets in experimental group exhibited significantly higher activities of superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GSH-Px)and total antioxidant capacity(T-AOC)(P<0.05),whereas malondialdehyde(MDA)concentration was significantly decreased(P<0.05).In conclusion,dietary supplementation with 120 mg/kg PE improved growth perfor-mance,enhanced intestinal development,and increased antioxidant capacity in weaned piglets.