息风止动方联合高频重复经颅磁刺激治疗小儿抽动症疗效观察OA

Objective:To observe the efficacy of Xifeng Zhidong formula combined with high-frequency repeti-tive transcranial magnetic stimulation(rTMS)in treating children with Tourette syndrome(TS).Methods:One hun-dred children with TS were selected and grouped using a random number table.All children received conventional psychotherapy and behavioral guidance.The control group was additionally treated with high-frequency rTMS,while the combination group was additionally treated with Xifeng Zhidong formula based on the control group's treatment.Both groups underwent continuous treatment for 4 weeks as one course.The two groups were compared on tradition-al Chinese medicine syndrome scores,inflammatory indicators[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)],Yale Global Tic Severity Scale(YGTSS)scores and Pediatric Quality of Life Inventory(PedsQL)scores before and after treatment,efficacy,and adverse reactions.Results:The combination group reported a total effective rate of 96.00％after treatment,notably higher than that reported by the control group(82.00％)(P＜0.05).The combi-nation group had notably lower traditional Chinese medicine syndrome scores than the control group after treatment(P＜0.05).Compared to the control group,the combination group exhibited notably lower levels of IL-6 and TNF-αafter treatment(P＜0.05).The combination group got notably lower YGTSS scores and notably higher PedsQL scores after treatment(P＜0.05).The overall incidence of adverse reactions did not differ notably between the groups(P＞0.05).Conclusion:Applying Xifeng Zhidong formula combined with high-frequency rTMS to treat chil-dren with TS can effectively improve traditional Chinese medicine syndromes,alleviate inflammation,and enhance the quality of life,with good safety.