臀部恶性单纯性汗腺棘皮瘤1例OA
A case of malignant hidroacanthoma simplex on the hip
报告臀部恶性单纯性汗腺棘皮瘤1例.患者女,85岁,左臀部斑块半年余.皮肤科检查:左臀部红褐色斑块,约3 cm×3 cm大小,边缘不规则,表面粗糙覆盖黑痂,部分破溃少许渗液.皮损组织病理示:表皮明显角化过度伴角化不全,棘层增生呈乳头瘤样,表皮中可见境界清楚的肿瘤团块,瘤细胞核深染,核仁明显,有丝分裂多见.免疫组化示:EMA(灶性+)、CK14(+)、CK20(个别细胞+)、Cam5.2(少数细胞+).诊断为恶性单纯性汗腺棘皮瘤.予手术切除治疗,随访1年未复发.
We report a case of malignant hidroacanthoma simplex on the hip.An 85-year-old female presented with a 6-month history of a papule on her left hip.Dermatological examination showed a brown-colored hyperkeratotic plaque measuring 3 cm × 3 cm with irregular margins and visible surface crusts.Histopathological examination revealed marked hyperkeratosis,acanthosis,papillomatosis,and well-circumscribed intraepidermal tumor nests.Atypical cells with large,hy-perchromatic nuclei and mitotic activity were observed within the tumor nests.Immunohistochemi-cal staining was positive for EMA,CK14,CK20(a few cells),and Cam5.2(a few cells)in the lesional skin.The diagnosis was malignant hidroacanthoma simplex.Complete excision was per-formed,and no recurrence was observed during the 12-month follow-up period.
何丽霞;刘迎红;翁立强;龙琴琴;陈柏叡
福州市皮肤病防治院,福建 福州 350025福州市皮肤病防治院,福建 福州 350025福州市皮肤病防治院,福建 福州 350025福州市皮肤病防治院,福建 福州 350025福州市皮肤病防治院,福建 福州 350025
单纯性汗腺棘皮瘤恶性
hidroacanthoma simplexmalignant
《皮肤性病诊疗学杂志》 2026 (2)
138-141,4
福州市卫生健康中青年人才科研项目(2022-S-rc3)
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