首页|期刊导航|皮肤性病诊疗学杂志|负压创面技术联合纳米银医用抗菌敷料治疗烧伤患儿的疗效

负压创面技术联合纳米银医用抗菌敷料治疗烧伤患儿的疗效OA

The efficacy of negative pressure wound therapy combined with nano-silver antibacterial dressings in the treatment of burn wounds in children

中文摘要英文摘要

目的 探究负压创面技术联合纳米银医用抗菌敷料治疗烧伤患儿的疗效.方法 选取2023年11月—2025年5月本院收治的烧伤患儿120例,随机分为对照组(60例)和观察组(60例),对照组采用负压创面技术治疗,观察组采用负压创面技术配合纳米银医用抗菌敷料治疗.治疗10 d后采用温哥华瘢痕量表(VSS)评估疤痕增生程度,采用视觉模拟量表(VAS)评估疼痛程度,采用ELISA检测患者治疗前及治疗10 d后血清中炎症因子CRP、IL-6、TNF-α、IL-8水平.同时比较两组患儿创面愈合时间、住院时间、换药次数.结果 观察组的创面愈合时间、住院时间、换药次数、VSS评分均低于对照组(P<0.05).治疗10 d后两组VAS评分及血清中CRP、IL-6、TNF-α、IL-8水平均较治疗前降低,且观察组均低于对照组(均P<0.05).结论 应用负压创面技术配合纳米银医用抗菌敷料治疗烧伤患儿可显著改善创面愈合情况,缓解其炎症反应和疼痛程度,加快患儿的康复进程.

Objective To explore the efficacy of negative pressure wound therapy combined with nano-silver antibacterial dressings in the treatment of burn wounds in children.Methods A total of 120 burned children admitted to our hospital from November 2023 to May 2025 were ran-domly divided into a control group(60 cases)and an observation group(60 cases).The control group was treated with negative pressure wound therapy,while the observation group was treated with negative pressure wound therapy combined with nano-silver medical antibacterial dressings.After 10 days of treatment,the vancouver scar scale(VSS)was used to assess the degree of scar hyperplasia,while the degree of pain was evaluated using the visual analogue scale(VAS)and the levels of inflammatory factors,including CRP,IL-6,TNF-α,and IL-8,were measured before treatment and 10 days after treatment using ELISA.Additionally,we compared the wound healing time,hospital stay,and dressing change frequency between the two groups.Results The wound healing time,hospital stay,dressing change frequency,and VSS score in the observation group were all significantly lower than those in the control group(P<0.05).After 10 days of treat-ment,the VAS scores and the levels of CRP,IL-6,TNF-α,IL-8 in the serum of patients in both groups were lower than those before treatment,with the observation group showing lower levels than the control group(all P<0.05).Conclusion The application of negative pressure wound therapy combined with nano-silver medical antibacterial dressings in the treatment of burned chil-dren can significantly improve wound healing,alleviate inflammation and pain,and accelerate the recovery process.

姜海洋;杨洪;马常明

南阳南石医院,河南 南阳 473000南阳南石医院,河南 南阳 473000南阳南石医院,河南 南阳 473000

烧伤负压创面技术纳米银医用抗菌敷料

burn woundsnegative pressure wound technologynano-silvermedical an-tibacterial dressings

《皮肤性病诊疗学杂志》 2026 (2)

87-91,5

10.3969/j.issn.1674-8468.2026.02.002

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