藏族超重、肥胖人群体成分与血清谷丙转氨酶及尿酸的相关性OA

Objective:To investigate the characteristics of body composition among the Tibetan population and to analyze the impact of overweight and obesity on serum alanine aminotransferase(ALT)and uric acid(UA)levels.The study also aimed to explore the correlations between body composition and ALT/UA among overweight and obese Tibetan individuals.Methods:A cluster random sampling method was used to select adult Tibetan residents in Lhasa,Tibet.Height and body composition were measured,and biochemical indicators including ALT and UA were assessed.The abnormal detection rates of ALT and UA were calculated.Results:Among Tibetan adults,the rates of overweight and obesity were 33.22%and 13.22%in males,and 39.65%and 20.19%in females,respectively.The abnormal detection rates of ALT and UA in males were 40.00%and 32.20%,and 17.27%and 12.90%in females.In overweight males,ALT levels were significantly positively correlated with height,body weight,fat mass,subcutaneous fat mass,and trunk fat mass.UA levels in overweight males were significantly positively correlated with trunk muscle mass and right upper limb muscle mass;In obese males,UA levels were significantly positively correlated with body mass index and body fat percentage.In overweight females,UA levels were significantly positively correlated with body fat percentage,visceral fat mass,trunk fat mass,and fat percentages of the left and right lower limbs.In obese females,UA levels were significantly positively correlated with visceral fat mass.Conclusion:The abnormal detection rates of ALT and UA were higher in overweight and obese Tibetan adult males compared with females.ALT levels were significantly positively correlated with muscle and fat indicators in overweight males.UA levels showed significant positive correlations with muscle indicators in overweight males and with fat-related indicators in obese males as well as in both overweight and obese females.