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功能成像驱动下的活体解剖学:从结构观察迈向功能理解OA

In vivo anatomy driven by functional imaging:From structural observation to functional understanding

中文摘要英文摘要

近年来,功能成像技术在解剖学研究领域逐渐引起广泛关注.不同于传统以大体解剖或静态结构影像为主的方法,功能成像能够在活体状态下实时监测器官组织的代谢状态、血流动力学及神经传导实时动态变化等,为深入理解"结构—功能"之间的关联提供了全新视角与技术平台.笔者以"结构观察向功能理解转变"为主线,系统梳理磁共振功能成像、正电子发射型计算机断层显像、超声及光学成像等代表性功能影像技术的研究进展与应用实例,总结其在临床术前规划、精准治疗、科研教学等方面的价值,并探讨当前面临的标准化、数据融合与图谱构建等挑战.

In recent years,functional imaging techniques have gradually attracted widespread attention in the field of anatomical research.Unlike traditional methods that primarily rely on cadaver dissection or static structural imaging,functional imaging enables real-time monitoring of the metabolic status,hemodynamics,and neural conduction in living organisms.This provides a new perspective and technological platform for a deeper understanding of the correlation between"structure and function".This article,following the theme of"transition from structural observation to functional understanding",systematically reviews the research progress and application examples of representative functional imaging techniques such as functional magnetic resonance imaging,positron emission tomography/computed tomography,ultrasound,and optical imaging.It also summarizes their value in clinical preoperative planning,precision treatment,scientific research,and education,and discusses the current challenges such as in standardization,data fusion,and atlas construction.

许锴;李舜尧;冯思嘉;王月明;沃雁;陈俊

复旦大学附属华山医院运动医学科,上海 200040复旦大学附属华山医院运动医学科,上海 200040复旦大学附属华山医院运动医学科,上海 200040上海交通大学医学院解剖学与生理学系,上海 200025上海交通大学医学院解剖学与生理学系,上海 200025复旦大学附属华山医院运动医学科,上海 200040

医药卫生

功能成像活体解剖学磁共振功能成像正电子发射型计算机断层显像光学成像精准医学

functional imagingin vivo anatomyfunctional magnetic resonance imagingpositron emission tomography/computed tomographyoptical imagingprecision medicine

《解剖学杂志》 2026 (1)

1-7,7

10.3969/j.issn.1001-1633.2026.01.001

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