PTH induced osteoblast Slit3 to decrease aberrant sensory innervation in degenerated vertebral endplates to relieve low back pain in miceOA

作者：Weixin Zhang;Arryn D.Otte;Zhuolun Wang;Sisir Kumar Barik;Mei Wan;Xu Cao;Janet L.Crane

作者单位：Department of Orthopedic Surgery,Johns Hopkins University School of Medicine,Baltimore,MD,USA||Division of Pediatric Endocrinology,Johns Hopkins University School of Medicine,Baltimore,MD,USADivision of Pediatric Endocrinology,Johns Hopkins University School of Medicine,Baltimore,MD,USADepartment of Neurology,Johns Hopkins University School of Medicine,Baltimore,MD,USADivision of Pediatric Endocrinology,Johns Hopkins University School of Medicine,Baltimore,MD,USADepartment of Orthopedic Surgery,Johns Hopkins University School of Medicine,Baltimore,MD,USADepartment of Orthopedic Surgery,Johns Hopkins University School of Medicine,Baltimore,MD,USADepartment of Orthopedic Surgery,Johns Hopkins University School of Medicine,Baltimore,MD,USA||Division of Pediatric Endocrinology,Johns Hopkins University School of Medicine,Baltimore,MD,USA

刊名：《骨研究（英文版）》 2026 (1)

页码/页数：152-165,14

基金：This research was supported by the U.S.Department of Health&Human Services NIH National Institute on Aging under Award Number P01AG066603(to J.C.).

DOI：10.1038/s41413-025-00488-z