抑郁状态人群中医体质分布特征OA

Objective To characterize the distribution of Traditional Chinese Medicine(TCM)body constitution types among individuals with depressive states of varying severity.Methods Using an online questionnaire,the Short-Form version of the Constitution in Chinese Medicine Questionnaire and the Patient Health Questionnaire-9(PHQ-9)were administered to adults aged 18 – 60 years from the general population.The correlation between TCM constitution types and the severity of depression was analyzed using Spearman's correlation coefficient.Results A total of 1,010 questionnaires were collected;297 invalid questionnaires were excluded,leaving 713 valid responsesm,162 were male and 551 were female.Among them,517(72.51%)were in a depressive state and 196(27.49%)were not depressed.In the 18–30 and 31–40 age groups,the proportion with depression was higher than the proportion without depression(P<0.05),and the proportion of women with depression was higher than that of men(P<0.05).Among those with depression,the main TCM constitution types were yangdeficiency(n=113,21.86%),qistagnation(n=109,21.08%),and balanced(n=83,16.05%).In mild and moderate depression,the common biased constitution types were yangdeficiency and qistagnation;in moderately severe and severe depression,qistagnation predominated.Correlation analysis showed that the top three TCM constitution types associated with depression severity were bloodstasis(r=0.513,P=0.015),qistagnation(r=0.504,P=0.000),and dampheat(r=0.457,P=0.003),all with positive correlations(P<0.05).Conclusion Depressive states appear more prevalent among young adults and more common in women than in men.Among individuals with depressive states,yang-deficiency and qi-stagnation were the predominant TCM constitution types.Both blood stasis and qi-stagnation showed positive associations with depression severity.Targeting biased TCM constitutions-particularly blood stasis and qi-stagnation-may aid prevention and management of depressive states.Because mild to moderate depressive states were mainly associated with yang-deficiency,early conditioning for yang-deficiency may be relevant to early prevention and treatment.