脑结构损伤、脑衰弱与脑龄在缺血性卒中预后评估中的价值OA
Brain structural damage,brain frailty,and brain age in the prognostic assessment of ischemic stroke
缺血性卒中后病人功能恢复存在明显个体差异,传统临床指标难以充分解释这种异质性.随着人工智能技术发展,基于神经影像的脑结构损伤、脑衰弱与脑龄等指标,为评估大脑健康储备及预后提供了新方向.本综述系统阐述了脑结构损伤、脑衰弱与脑龄的定义、评估方法及临床意义,并分析其相互关系.深入理解三者关系,有助于更精准解析卒中后功能恢复的个体差异,对于构建多维度预后预测体系、推动卒中精准医疗具有重要作用.
Functional recovery after ischemic stroke exhibits considerable interindividual variation that conventional clinical measures often fail to fully explain.Advances in artificial intelligence have enabled novel neuroimaging-based approaches.Metrics such as brain structure damage,brain frailty,and brain age offer new perspectives for assessing brain health reserve and predicting outcomes.This review systematically outlines the definitions,assessment methods,and clinical relevance of brain structure damage,brain frailty,and brain age,and examines their interrelationships.A deeper understanding of these relationships may allow more precise interpretation of individual differences in post-stroke recovery,providing valuable insights for establishing a multidimensional prognostic prediction system and advancing precision medicine in stroke care.
李佳楠;赵思嘉;朱武生;程晓青
南京大学医学院附属金陵医院/东部战区总医院放射诊断科,南京 210002徐州医科大学医学影像学院南京大学医学院附属金陵医院/东部战区总医院神经内科南京大学医学院附属金陵医院/东部战区总医院放射诊断科,南京 210002
医药卫生
缺血性卒中脑结构脑衰弱脑龄磁共振成像
Ischemic strokeBrain structureBrain frailtyBrain ageMagnetic resonance imaging
《国际医学放射学杂志》 2026 (2)
185-189,5
国家自然科学基金项目(82271983)
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