基于脑肠轴理论观察揿针治疗儿童单纯性肥胖脾虚湿阻证临床疗效OA

Objective:To observe the clinical efficacy of thumbtack needle therapy based on the brain-gut axis theory in treating pediatric simple obesity of syndrome of spleen deficiency with damp retention.Methods:A ret-rospective study was conducted on 72 pediatric patients with simple obesity of syndrome of spleen deficiency with damp retention admitted to the First Affiliated Hospital of Henan University of Chinese Medicine from January 2022 to November 2023.They were divided into observation group and control group,with 36 cases in each group,according to different treatment regimens.The control group received dietary regulation and exercise therapy,while the observation group received thumbtack needle therapy on this basis.After 2 months of treat-ment,the two groups were compared in terms of TCM symptom scores,obesity indicators[body weight,BMI,fat percentage(F％)],clinical efficacy,blood lipid levels[total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),and high-density lipoprotein cholesterol(HDL-C)],glucose me-tabolism[fasting blood glucose(FBG),fasting insulin(FIN),insulin resistance index(HOMA-IR)],and adverse reactions(needle faintness,local allergy,etc).Results:After treatment,the TCM symptom scores in the observation group were superior to those in the control group(P＜0.05);body weight,BMI,and F％in the observation group were better than those in the control group(P＜0.05);the total effective rate in the observa-tion group was 97.22％(35/36),which was higher than that in the control group[83.33％(30/36)](P＜0.05);the levels of TC,TG,and LDL-C in the observation group decreased significantly compared with pre-treatment(P＜0.05),while the level of HDL-C increased significantly compared with pretreatment(P＜0.05),and the observation group were superior to the control group(P＜0.05);the levels of FBG,FIN,and HOMA-IR in the observation group were superior to those in the control group(P＜0.05).No adverse reac-tions such as needle faintness,local allergy,or gastrointestinal discomfort occurred in either group of patients during treatment.Conclusion:Based on the brain-gut axis theory,thumbtack needle therapy for pediatric sim-ple obesity of syndrome of spleen deficiency with dampness retention can alleviate clinical symptoms,reduce body fat accumulation and blood lipid levels,promote glucose metabolism,enhance insulin sensitivity,and thus control obesity with good safety.