基于"治之以兰,除陈气也"辨治多囊卵巢综合征合并胰岛素抵抗OA
Treatment of Polycystic Ovary Syndrome Complicated with Insulin Resistance Based on the Principle of"Treating with Orchid-Flavored Herbs to Eliminate Stagnant Pathogenic Qi"
多囊卵巢综合征合并胰岛素抵抗(PCOS-IR)是一种以女性生殖及内分泌代谢异常为特征的常见疾病.由于高胰岛素分泌导致卵巢功能亢进,出现高雄激素、持续无排卵、卵巢呈多囊改变,临床常表现为月经周期紊乱、肥胖、多毛、痤疮等.《黄帝内经》提出"治之以兰,除陈气也",描述对脾瘅病的治疗方法,脾瘅核心病机为脾虚湿盛,强调代谢异常为其关键因素,以胰岛素抵抗为其发病中心环节.PCOS-IR的核心病机亦为"脾虚湿蕴,陈气瘀滞",本文结合"治之以兰,除陈气也"理论,制定芳香祛湿、健脾益气的治疗大法,运用藿朴夏苓汤加减,以调节糖脂代谢,达到"除陈气"的目的,同时附验案1则,为PCOS-IR的诊治提供新的思路和方法.
Polycystic ovary syndrome combined with insulin resistance(PCOS-IR)is a common disease mainly characterized by abnormalities in the female reproductive system and endocrine-metabolic system.Hyperinsuli-nemia leads to ovarian hyperfunction,resulting in hyperandrogenism,persistent anovulation,and polycystic ovar-ian changes.Clinically,it often shows as menstrual cycle disorders,obesity,hirsutism,acne,etc.Huangdi Neijing proposes"treating with orchid-flavored herbs to eliminate stagnant pathogenic qi"describing the treat-ment method for spleen-heat syndrome.The core pathogenesis of spleen-heat syndrome is spleen deficiency and dampness accumulation,emphasizing metabolic abnormalities as the key factor,with insulin resistance as the central link in its pathogenesis.The core pathogenesis of PCOS-IR is also"spleen deficiency,dampness accu-mulation,and stagnant qi"This article combines the theory of"treating with orchid-flavored herbs to eliminate stagnant pathogenic qi"clarifies the general treatment method of dispelling dampness with fragrant herbs and strengthening spleen qi,and uses modified Huopo Xialing Decoction to regulate glucose and lipid metabolism,achieving the goal of"eliminating stagnant qi"Simultaneously attach one case for verification and offer new ideas and methods for the diagnosis and treatment of PCOS-IR.
刘怡梦;吴薇薇;李晓慧;张淑芬;李新玲
山西中医药大学,山西太原 030024山西中医药大学,山西太原 030024山西省中医药研究院/山西省中医院,山西太原 030012山西省中医药研究院/山西省中医院,山西太原 030012山西省中医药研究院/山西省中医院,山西太原 030012
医药卫生
治之以兰除陈气多囊卵巢综合征胰岛素抵抗脾瘅藿朴夏苓汤理论探讨
Treating with orchid-flavored herbsEliminate stagnant pathogenic qiPolycystic ovary syndromeInsulin resistanceSpleen-heat syndromeHuopo Xialing DecoctionTheoretical discussion
《国医论坛》 2026 (1)
15-19,5
国家自然科学基金项目(22176116)第五批全国中医临床优秀人才研修项目资助(国中医药人教函[2022]1号).
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