Tau impedes glioma progression by enhancing fatty acidβ-oxidation-induced cellular senescenceOACSCDCSTPCD
Tau impedes glioma progression by enhancing fatty acidβ-oxidation-induced cellular senescence
Wan-Hong Han;Yuan-Yuan Xie;Yan-Yan Geng;Bing-Chang Zhang;Zhan-Xiang Wang;Wu-Jie Zhao;Jia-Wei He;Wen-Peng Zhao;Han-Wen Lu;Zhen-Wei Lu;Xian-Sheng Qiu;Chen Chang;Ya-Ya Zhang
Department of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,School of Medicine,Xiamen University,Xiamen,Fujian 361102,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,Fujian Medicine University,Fuzhou,Fujian 350122,ChinaDepartment of Neurosurgery and Department of Neuroscience,Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment,Xiamen Key Laboratory of Brain Center,the First Affiliated Hospital of Xiamen University,Fujian Medicine University,Fuzhou,Fujian 350122,ChinaDepartment of Pathology,Shaanxi Provincial People's Hospital,Xi'an,Shaanxi 710068,ChinaDepartment of Medical Oncology,the First Affiliated Hospital of Xiamen University,Xiamen,Fujian 361102,China
GliomaTauCPT1ACellular senescenceFatty acid β-oxidation
GliomaTauCPT1ACellular senescenceFatty acid β-oxidation
《动物学研究》 2025 (6)
1304-1316,13
This work was supported by the National Natural Science Foundation of China(82072777),Fujian Provincial Clinical Research Center for Brain Diseases(2021FJSLCYX01),Xiamen Clinical Research Center for Neurological Diseases(2021XMSLCYX01)Project of Xiamen Cell Therapy Research(3502Z20214001),and Raman Medical Collaboration Project of the First Affiliated Hospital of Xiamen University(XFLM2023005)
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