Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9OA
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Wei Chen;Sijing Shi;Yuanlong Su;Shan Gao;Wei Huang;Xunde Xian;Jiangning Liu;Yuhui Wang;Yuanwu Ma;Xu Zhang;Rui Fan;Xia Li;Feifei Guan;Gefan Wan;Weining Kong;Xiaolong Qi;Shuo Pan
State Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaInstitute of Cardiovascular Sciences,State Key Laboratory of Vascular Homeostasis and Remodeling,School of Basic Medical Sciences,Peking University,Beijing,ChinaInstitute of Cardiovascular Sciences,State Key Laboratory of Vascular Homeostasis and Remodeling,School of Basic Medical Sciences,Peking University,Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,China||Haihe Laboratory of Cell Ecosystem,Tianjin,ChinaInstitute of Cardiovascular Sciences,State Key Laboratory of Vascular Homeostasis and Remodeling,School of Basic Medical Sciences,Peking University,Beijing,ChinaInstitute of Cardiovascular Sciences,State Key Laboratory of Vascular Homeostasis and Remodeling,School of Basic Medical Sciences,Peking University,Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaInstitute of Cardiovascular Sciences,State Key Laboratory of Vascular Homeostasis and Remodeling,School of Basic Medical Sciences,Peking University,Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,China||Haihe Laboratory of Cell Ecosystem,Tianjin,China||Medical Primate Research Center,Chinese Academy of Medical Sciences,Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaInstitute of Cardiovascular Sciences,State Key Laboratory of Vascular Homeostasis and Remodeling,School of Basic Medical Sciences,Peking University,Beijing,ChinaDepartment of Laboratory Animal Science,Peking University Health Science Center,Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,ChinaState Key Laboratory of Respiratory Health and Multimorbidity,NHC Key Laboratory of Human Disease Comparative Medicine,Key Laboratory of Pathogen Infection Prevention and Control,Ministry of Education,National Human Diseases Animal Model Resource Center and National Center of Technology Innovation for Animal Model,Institute of Laboratory Animal Science,Chinese Academy of Medical Sciences(CAMS),Peking Union Medical College(PUMC),Beijing,China
conditional knockoutgenome editingGolden Syrian hamster
conditional knockoutgenome editingGolden Syrian hamster
《动物模型与实验医学（英文）》 2026 (2)
308-318,11
State Key Laboratory Special Fund,Grant/Award Number:2060204Open Research Project in State Key Laboratory of Vascular Homeostasis and Remodeling,Grant/Award Number:Peking University,202411The Non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences,Grant/Award Number:2023-PT180-01Haihe Laboratory of Cell Ecosystem Innovation Fund,Grant/Award Number:HH24KYZX0007CAMS Innovation Fund for Medical Sciences,Grant/Award Number:2021-I2M-1-024,2022-I2M-1-020 and 2023-I2M-2-001the National Key Research and Development Program of China from the Ministry of Science and Technology,Grant/Award Number:2021YFF0702802
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