肺动脉CTA虚拟单能成像赋能放射科技师:基于血栓显示优选能级提升肺动脉栓塞预警信心的研究OA
Virtual Monoenergetic Imaging of Pulmonary CT Angiography Empowers Technologists:Improvement of Pulmonary Embolism Alerting by Energy Level Optimization Based on Thrombi Presentation
目的:基于图像质量和血栓显示优选虚拟单能成像(VMI)肺动脉CT造影(PCTA)能级并评估其对于放射科技师预警肺动脉栓塞(PE)信心的影响.方法:前瞻性筛选 2025年 2月至 2025年 3月在本院因临床医师怀疑存在肺动脉栓塞而接受PCTA检查的患者,均使用双源双能CT进行PCTA检查,重建为 120 kVp等效混合能量(PEI)图像和 70、60、50和 40 keV能级的VMI图像.1名放射科技师进行客观测量,测量升主动脉、肺动脉干、肺动脉左支、肺动脉右支、左肺下叶分支、右肺下叶分支、肝实质和竖脊肌,获得CT值(HU)及其标准差(SD),计算信号噪声比(SNR);以竖脊肌的SD值作为背景噪声,计算对比噪声比(CNR).2名放射科技师对 23名有血栓患者的图像,采用 5 分法评价其对预警PE的信心,5分为十分肯定存在血栓,必须通知诊断医师立即阅片确认,发布危急值;1分为无法发现存在血栓,无需通知诊断医师提前阅片.比较不同组图像之间客观和主观评价之间的差异.结果:研究共纳入 98名患者,年龄(72.06±13.41)岁,男性 47名,女性 51名;其中 23名存在血栓,75名患者不存在血栓.客观测量显示,40、50和 60 keV的VMI图像中,随着VMI图像能级的降低,相应的CT值随之上升,可以提供较好的组织对比度,但SD值也随之上升,提示较大的噪声.40 keV和 50 keV的VMI图像中,血管和血栓的CNR值均高于PEI图像.主观评价中,技师能发现几乎所有血栓(225/230,97.8%),但技师观察 50 keV VMI图像时对于预警PE较PEI图像更有信心((4.72±0.58)vs.(4.41±0.88)).结论:针对PCTA检测PE的临床任务可以优选50 keV VMI图像,提高技师预警PE的信心,有利于技师及时提示医师阅片确认并发布危急值,具有改善患者的临床诊疗流程的潜力.
Objective:To optimize the virtual monoenergetic imaging(VMI)energy level for pulmonary computed tomography(CT)angiography(PCTA)based on image quality and thrombus visualization and evaluate its impact on the confidence of radiological technologists in detecting pulmonary embolism(PE).Methods:Patients who underwent PCTA because of clinical suspicion of PE at our hospital between February 2025 and March 2025 were prospectively screened.All examinations were performed using dual-source dual-energy CT,and the images were reconstructed into 120 kVp equivalent polyenergetic imaging(PEI)and VM images at energy levels of 70,60,50,and 40 keV.One radiological technologist conducted objective measurements to assess the ascending aorta,main pulmonary artery,left pulmonary artery branch,right pulmonary artery branch,right lower lobe pulmonary artery branch,left lower lobe pulmonary artery branch,liver parenchyma,and erector spinae muscle to obtain CT values(Hounsfield units[HU])and their standard deviations(SD)to calculate the signal-to-noise ratio(SNR).The contrast-to-noise ratio(CNR)was calculated using the SD value of the erector spinae muscle as the background noise.Two radiological technologists evaluated the images of 23 patients with thrombi using a 5-point scale to assess their confidence in alerting them to PE.A score of 5 denoted a high certainty of thrombus presence,necessitating immediate notification to the diagnostic physician for review and issuance of a critical value,whereas a score of 1 denoted no thrombus detection,requiring no prior review by the diagnostic physician.Differences in objective and subjective assessments between the different image groups were compared.Results:The study included 98 patients,with a mean age of(72.06±13.41)years,comprising 47 male and 51 female patients;23 had thrombi and 75 did not.Objective measurements revealed that in the 40,50,and 60 keV VMI images,as the VMI energy level decreased,the corresponding CT values increased,providing improved tissue contrast.However,the SD values also increased,indicating higher noise levels.In the 40 and 50 keV VMI images,the CNR values for the vessels and thrombi were higher than those in the PEI images.Subjective assessment showed that the two technologists detected almost all thrombi(225/230,97.8%),but had greater confidence in alerting PE when observing 50 keV VMI images than when observing PEI images((4.41±0.88)vs.(4.72±0.58)).Conclusion:For the clinical task of detecting PE using PCTA,50 keV VMI images are preferred to enhance the confidence of radiological technologists in alerting patients with PE,facilitating timely physician review and issuance of critical values,with the potential to improve clinical diagnoses and the treatment process for patients.
陈黎伟;王思连;代顺;许芷菡;宋阳;褚敬申;张欢;姚伟武;钟京谕
上海交通大学医学院附属同仁医院影像科,上海 200336||上海市柔性医疗机器人重点实验室,上海 200336上海交通大学医学院附属同仁医院影像科,上海 200336||上海市柔性医疗机器人重点实验室,上海 200336上海交通大学医学院附属同仁医院影像科,上海 200336||上海市柔性医疗机器人重点实验室,上海 200336西门子医疗 诊断影像CT科研合作部,上海 200126西门子医疗 磁共振科研市场部,上海 200126上海交通大学医学院附属瑞金医院 科技发展处《诊断学理论与实践》编辑部 放射科,上海 200050上海交通大学医学院附属瑞金医院 放射科,上海 200050上海交通大学医学院附属同仁医院影像科,上海 200336||上海市柔性医疗机器人重点实验室,上海 200336上海交通大学医学院附属同仁医院影像科,上海 200336||上海市柔性医疗机器人重点实验室,上海 200336
医药卫生
CT肺动脉造影X线计算机体层摄影虚拟单能量成像图像质量
pulmonary CT angiographyX-ray computed tomographyvirtual monoenergetic imagingimage quality
《CT理论与应用研究》 2026 (2)
239-248,10
国家自然科学基金(基于CT增强影像组学联合代谢组学构建急性胰腺炎重症化智能早期预警模型研究(82302183)基于注意力-可解释图文信息挖掘创建膝骨关节炎交互式诊断报告系统(82471935)厌氧消化链球菌重塑局部进展期直肠癌免疫微环境及MR预测模型研究(82271934))上海市卫生健康委员会项目(骨病多模态报告和数据系统(Bone-RADS)规范精准风险评估并优化诊疗管理建议的临床研究(20244Y0214))上海市长宁区科学技术委员会项目(基于肺动脉CT血管造影等多参数构建急性肺栓塞后血栓残留预测模型研究(CNKW2024Y07)).
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