1例肉鸡马立克氏病疫情中80只病鸡的临床诊断与中药辅助治疗OA

In August-September 2024,an outbreak occurred in a broiler farm.This study selected 80 diseased chickens as research subjects,and conducted clinical diagnosis and adjunctive treatment with 3 traditional Chinese medicine(TCM)prescriptions:Longdan Xiegan decoction(containing Gentiana scabra,Scutellaria baicalensis,Gardenia jasminoides,etc.),Qingwen Baidu powder(containing Lophatherum gracile,Glycyrrhiza uralensis,Platycodon grandiflorus,etc.),and Chigui Wuwen powder(containing Radix Lsatidis,Lonicera japonica,Forsythiae fructus,etc.).In terms of clinical manifestations,athe diseased chickens showed severe emaciation and limb paralysis.At necropsy,diffuse tumors were observed in the liver and spleen,with unilateral enlargement of the ischiadic nerve.Marek's disease(MD)was confirmed by diagnostic methods including PCR detection and kit re-verification.Adjunctive TCM therapy has demonstrated that all 3 TCM formulae exhibited potential therapeutic effects against MD in broilers.The clinical symptoms of the affected chickens were significantly ameliorated,and the mortality rate was markedly reduced(P<0.05).The serum levels of total protein and globulin were significantly increased,while the activities of aspartate aminotransferase and alanine aminotransferase were significantly decreased(P<0.05).In conclusion,these TCM formulae show promising potential in the prevention and treatment of MD in broilers,and can also promote the growth performance of broilers,thus possessing certain popularization and application value in practical production.