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移植外科的范式变革:迈向数智化新征程OA

The paradigm shift in transplant surgery:navigating the digital and intelligent frontier

中文摘要英文摘要

数智化浪潮正推动移植外科发生系统性、范式性的深刻变革.在认知层面,影像组学、数字孪生与多组学整合分析推动评估方式由"结构可视"向"功能预测"跨越,实现对供受体状态的全局评估,并为异种移植的供体筛选与免疫风险预测开辟了新路径.在执行层面,手术机器人、扩展现实与智能感知技术的深度融合,突破了传统外科操作的生理局限,显著提升手术精准度与可控性.在管理层面,基于液体活检、智能随访及个体化用药,构建了从"被动响应"到"主动干预"的术后调控体系,实现对排斥反应与并发症的前瞻性防控.在发展层面,数智化正驱动科研范式、培训路径、人才体系与协作模式发生根本性变革,催生复合型医师科学家群体与协同创新网络,逐步塑造出数据驱动的智慧移植新生态.

The ongoing wave of digitalization and intellectualization is driving a profound systemic and paradigmatic transformation in transplant surgery.This article elaborates how these technologies empower the field across multiple dimensions:cognitively,the integration of radiomics,digital twins,and multi-omics shifts evaluation from"structural visualization"to"functional prediction,"enabling holistic donor-recipient assessment and creating new pathways for donor selection and immune risk prediction in xenotransplantation;operationally,the deep integration of surgical robotics,extended reality,and intelligent sensing transcends physiological constraints,significantly enhancing procedural precision and controllability;in management,leveraging liquid biopsy,intelligent follow-up,and personalized medication establishes a postoperative system that evolves from"passive response"to"active intervention,"enabling proactive control of rejection and complications;developmentally,these technologies are reshaping research paradigms,training pathways,talent frameworks,and collaboration models,catalyzing the emergence of hybrid physician-scientists and collaborative innovation networks,and fostering a data-driven smart transplant ecosystem.

窦科峰;许皓

空军军医大学西京医院肝胆外科空军军医大学异种移植转化研究院,陕西西安 710032空军军医大学西京医院肝胆外科空军军医大学异种移植转化研究院,陕西西安 710032

医药卫生

器官移植数智化人工智能异种移植精准医疗

organ transplantationdigitalization and intellectualizationartificial intelligencexenotransplantationprecision medicine

《中国实用外科杂志》 2026 (1)

1-5,5

National Key Research and Development Program of China(No.2017YFC1103703)National Natural Science Foundation of China(No.82588101,No.82371793,No.82400666)Shaanxi Special Support Program for High-Level TalentsYoung Talent Fund of Association for Science and Technology in Shaanxi(No.20250308) 国家重点研发计划项目(No.2017YFC1103703)国家自然科学基金项目(No.82588101,No.82371793,No.82400666)陕西省高层次人才特殊支持计划项目陕西省科学技术协会青年人才托举计划项目(No.20250308)

10.19538/j.cjps.issn1005-2208.2026.01.01

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