基于数据挖掘探讨针刺治疗视神经萎缩选穴规律OA

OBJECTIVE To analyze the clinical acupoint selection patterns in acupuncture treatment for optic nerve atrophy based on data mining technology.METHODS Clinical research literature on acupuncture treatment for optic nerve atrophy was retrieved from the China National Knowledge Infrastructure(CNKI),Wanfang,and VIP databases up to October 31st,2024.The publication time,title,author,and acupoint prescriptions of the included literature were entered into Excel 2016 software to establish a database.Acupoints were classified and counted according to the meridians they belong to,and their usage frequency was recorded.IBM SPSS Modeler 18.0 software was used to analyze association rules of acupoints,and the clustering analysis function of Origin 2021 software was employed to perform visual multidimensional analysis on high-frequency acupoints,generating a phylogenetic tree.RESULTS(1)General information:A total of 203 articles were included.The analysis involved 12 meridians and 104 acupoints,with a cumulative usage frequency of 2,816 times.Acupoints with a usage frequency of 22 times or more were considered high-frequency,totaling 24 acupoints.(2)Meridian statistics:Three meridians each contained three or more high-frequency acupoints used in acupuncture treatment for optic nerve atrophy.The Bladder Meridian of Foot-Taiyang,the Gallbladder Meridian of Foot-Shaoyang,and the Stomach Meridian of Foot-Yangming.Additionally,seven meridians had a usage frequency of 100 times or more.The top five were Bladder Meridian of Foot-Taiyang(451 times,24.95%),Stomach Meridian of Foot-Yangming(270 times,14.97%),extra points(237 times,13.11%),Gallbladder Meridian of Foot-Shaoyang(211 times,11.67%),and Kidney Meridian of Foot-Shaoyin(142 times,7.85%).(3)High-frequency acupoint frequency statistics:The top five acupoints by usage frequency were Jingming(BL1,152 times,8.41%),Fengchi(GB20,145 times,8.02%),Qiuhou(EX-HN7,126 times,6.97%),Chengqi(ST1,115 times,6.36%),and Zusanli(ST36,115 times,6.36%).(4)High-frequency acupoint association rules:The top five correlations with the highest confidence were Jingming(BL1)-Chengqi(ST1),Jingming(BL1)-Zusanli(ST36),Zusanli(ST36)-Sanyinjiao(SP6),Jingming(BL1)-Sanyinjiao(SP6),and Shenshu(BL23)-Ganshu(BL18).(5)High-frequency acupoint cluster analysis:Six core prescription groups were identified.Their functions were respectively Directing Jing(Essence),Qi,and blood upward to the eyes,regulating Qi,blood,and meridians around the eyes,clearing and regulating Yangming to brighten the eyes,soothing liver and regulating Qi,activating blood and dispelling stasis and tranquilizing and relieving pain.CONCLUSIONS The principle of acupoint selection in acupuncture treatment for optic nerve atrophy primarily employs the method of combining distal and local points.Points are frequently selected from the three Yang meridians,treating the eye system in conjunction with the whole body´s meridian system.The main treatment principles are tonifying Qi and blood,supplementing liver and kidney,unblocking collaterals,and brightening the eyes.