湖北省医疗机构抗流感病毒药物合理使用指引(2026年版)OA

Influenza viruses are currently experiencing seasonal high activity in Hubei Province,posing a major public health threat to the population.High-risk groups,such as the elderly,children,pregnant women,patients with chronic diseases,and individuals with compromised immune systems,are more susceptible to severe complications,including respiratory failure,multi-organ dysfunction,and even death.To further standardize the clinical use of anti-influenza antiviral agents,promote their rational application medical institutions at all levels within Hubei Province,reduce the risk of antiviral resistance,and ensure the safety,effectiveness,cost-effectiveness,and appropriateness of pharmacotherapy,the Hubei Provincial Clinical Pharmacy Quality Control Center convened a multidisciplinary expert panel in influenza diagnosis and treatment and clinical pharmacy to develop the Guide-line for the Rational Use of Anti-Influenza Antiviral Agents(hereinafter referred to as"the Guideline").This Guideline was formu-lated based on a systematic review of the latest evidence-based medical literature,drug prescribing information,and clinical prac-tice experience.,incorporating the epidemiological characteristics and healthcare context of Hubei Province.The Guideline applies to healthcare professionals involved in clinical diagnosis and treatment,pharmaceutical services,infection control,and related man-agement activities across all levels and types of medical institutions in Hubei Province.It focuses on key aspects including precise indication assessment,optimal timing of administration,individualized drug selection,dosage adjustment,treatment-course manage-ment,and medication use in special populations,aiming to provide scientific,practical,and implementable guidance for clinical practice.