现代医学背景下原发性肥胖症的中医认识及诊疗刍议OA
Traditional Chinese Medicine's Understanding and Diagnosis and Treatment of Primary Obesity in the Context of Modern Medicine:A Preliminary Discussion
原发性肥胖症是医学界面临的重大难题,现有减重西药并不能满足全部类型肥胖症的治疗需求.中医药治疗原发性肥胖症具有丰富的理论经验和临床实践基础,开发潜力较大.本文在《黄帝内经》"脂人、膏人、肉人"肥胖三型认识的基础上拓展了"小膏人"和"脂膏人"的分型,构建肥胖五型新分类体系,突破了现代医学以单一指标认识肥胖症的局限.并根据原发性肥胖症的异质性特点,从基于能量代谢特征的实壅、虚壅论治,实壅以厚朴三物汤为核心方,根据胃肠饥饿型、情绪饥饿型、脑饥饿型分类辨治;虚壅以六君子汤为核心方,根据低代谢型特点辨治.通过凝练核心病机,归纳核心方药,从而提高中医治疗的精准性,与现有减重西药形成优势互补,提高肥胖症临床疗效.
Primary obesity remains a major challenge confronting the medical community,and existing Western weight-loss medi-cations fail to address the therapeutic needs of all obesity subtypes.Traditional Chinese Medicine(TCM)possesses a robust foundation of theoretical insights and clinical practices in the management of primary obesity,exhibiting substantial potential for further develop-ment and application.This article expands on the understanding of the three types of obesity—"Zhi Ren,Gao Ren and Rou Ren"—de-scribed in The Yellow Emperor's Inner Classic,adding"Xiao Gao Ren"and"Gao-Zhi Ren"types to construct a new five-type classifi-cation system for obesity,aiming to overcome the limitations of modern medicine's single-indicator approach to understanding obesity.In light of the heterogeneous nature of primary obesity,this study proposes a treatment strategy based on the pathogenesis of excessive stagnation and deficiency-related stagnation characterized by energy metabolism profiles.For excessive stagnation,Houpo Sanwu De-coction is employed as the core formula,with further differentiation and treatment tailored to three subtypes:gastrointestinal hunger type,emotional hunger type and cerebral hunger type.For deficiency-related stagnation,Liujunzi Decoction serves as the foundational prescription,with syndrome differentiation and treatment customized according to the characteristics of the hypometabolic type.By ex-tracting core pathogenesis and refining core formulas,the precision of TCM treatment is improved,complementing existing Western weight-loss medications and enhancing the clinical efficacy of obesity treatment.
顾成娟;王涵;仝小林
甘肃中医药大学基础医学院,甘肃 兰州 730000||广州中医药大学深圳医院(福田),广东 深圳 518034北京中医药大学中药学院,北京 100029中国中医科学院广安门医院,北京 100053
医药卫生
原发性肥胖症肥胖异质性壅态分类辨治态靶黄帝内经肥胖五型
primary obesityobesity heterogeneitystagnation stateclassification-based syndrome differentiation and treatmentstate-targetThe Yellow Emperor's Inner Classicfive-type classification of obesity
《南京中医药大学学报》 2026 (2)
165-172,8
国家自然科学基金重点项目(82530125)中国科协青年人才托举工程项目(CACM-2024-QNRC1-01)深圳市"医疗卫生三名工程"仝小林院士中医代谢病团队项目(SZZYSM202202010)
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