育龄女性体力活动水平及静坐时间与月经周期异常的关联研究OA

Objective:To explore the relationship between physical activity,sedentary time,and irregular menstrual cycles in women of reproductive age.Methods:Conducted between April and June 2024 using convenience sampling,the cross-sectional study assessed physical activity and sedentary time through the international physical activity questionnaire-short form(IPAQ-SF),while menstrual cycles were self-reported.Associations were analyzed using logistic regression and restricted cubic spline models,with E-values calculated to assess the influence of potential unmeasured confounders.Results:A total of 1 259 participants were included,with a mean age of 25.0±5.3 years.The moderate physical activity was linked to a 40%lower risk of irregular menstrual cycles compared to low activity(OR=0.60,95%CI:0.44-0.81),and high physical activity was associated with a 46%reduced risk(OR=0.54,95%CI:0.37-0.79),after adjusting for all covariates.Meeting World Health Organization guidelines for moderate-to-vigorous activity was associated with a 36%decreased risk(OR=0.64,95%CI:0.48-0.85).No statistically significant association was observed between sedentary time and irregular menstrual cycles.E-value analysis suggested that unmeasured confounders would need a moderate association strength(1.8-2.1)with both exposure and outcome to negate these findings.The risk of irregular menstrual cycles began to rise when weekly total metabolic equivalents exceeded 3 185 min.Conclusion:Moderate to high physical activity levels are inversely related to irregular menstrual cycles in reproductive-aged women,though excessively high activity may increase risk.Ensuring adequate physical activity appears more crucial than merely reducing sedentary behavior.