首页|期刊导航|临床眼科杂志|原发性闭角型青光眼经白内障超声乳化联合房角分离术后房角结构参数的变化

原发性闭角型青光眼经白内障超声乳化联合房角分离术后房角结构参数的变化OA

Changes in angle structural parameters of primary angle closure glaucoma after phacoemulsification com-bined with Goniosynechialysis

中文摘要英文摘要

目的 研究原发性闭角型青光眼(PACG)经白内障超声乳化吸除联合房角分离术(Phaco+IOL+GSL)术后房角结构参数的变化,评估该手术的长期疗效.方法 回顾性病例研究.收集45例(45只眼)PACG患者.采集入组患者术前、术后1个月以及术后1年的眼压以及眼前节OCT图像,统计其房角结构参数数据,包括前房深度(ACD)、距巩膜突500 μm 处前房角度(ACA500)、距巩膜突 500 μm 处房角开放距离(AOD500)、距巩膜突 750 μm处房角开放距离(AOD750)、距巩膜突 500 μm 处小梁网虹膜间隙面积(TISA500)、距巩膜突750 μm处小梁网虹膜间隙面积(TISA750).分析各个参数术前术后的变化,对比不同时间段该参数的差异.结果 入组患者均接受了白内障超声乳化联合房角分离术,术后眼压较术前明显降低,差异具有统计学意义(P<0.0001),术后1个月眼压与术后1年眼压相比,差异无统计学意义(P>0.05).术后房角结构参数ACD、ACA500、AOD500、AOD750、TISA500、TISA750均较术前明显增大,差异均有统计学意义(P<0.0001),且术后1年与术后1个月各个房角结构参数相比差异均无计学意义,(P>0.05),且以上各个参数均与眼压均呈负相关.结论 PACG患者在接受Phaco+IOL+GSL术后眼压较前明显降低,房角结构参数较术前增加.术后1个月与术后1年PACG患者的房角结构参数变化差异无显著性,说明Phaco+IOL+GSL该手术方式具有长期有效性,可以从恢复房水生理性引流通道来治疗PACG.

Objective To evaluate the long-term effectiveness of this surgical procedure by studying the changes of angle structural parameters of primary angle closure glaucoma(PACG)patients who underwent phacoemulsification catatact surgery combined with goniosynechialysis.Methods This was a retrospective study.45 PACG patients 45 eyes.Collecting all Iop and AS-OCT images of these patients(included before surgery,at 1 month and 1 year after the surgery in this study).Organizing these parameters data.Measurement parameters included anterior chamber depth(ACD),anterior chamber angle 500 μm(ACA500),angle opening distance 500 μm(AOD500),angle opening distance at 750 μm(AOD750),trabecular-iris space area 500 μm(TISA500),trabecular-iris space area 750 μm(TISA750).Analyzed the changes of these parameters before and after the surgery,compare the differences in these parameters at differene time.Re-sults 45 patients underwent phacoemulsification combined with goniosynechialysis.None of them were on intraocular pressure(IOP)-lowering medication postoperatively.Postoperative IOP was significantly lower than preoperative IOP(P<0.0001).The difference in IOP at one month postoperatively compared to one year postoperatively was not statistically sig-nificant(P>0.05).Postoperative angle structural parameters:ACD,ACA500,AOD500,AOD750,TISA500,TISA750 were all increased significantly compared to the preoperative period.The difference was statistically significant(P<0.0001).Differences in individual these angle structural parameters at one month postoperatively compared with one year postoperatively were not statistically significant(P>0.05).All parameters are negatively correlated with IOP.Conclu-sions The IOP of patients with primary angle closure glaucoma had a reduction after undergoing phacoemulsification com-bined with goniosynechialysis,and these angle structural parameters,were significantly increased compared to preopera-tive.The difference between 1 month and 1 year after the surgery was not significant,indicating that the Phaco+IOL+GSL has a long-term impact,and that this operation can be used to treat PACG by restoring the functionality of the channel of aqueous humor.

徐琳琳;周熠;翟浩宇;郭建新

221002 江苏徐州,徐州医科大学附属医院眼科221002 江苏徐州,徐州医科大学附属医院眼科221002 江苏徐州,徐州医科大学附属医院眼科221002 江苏徐州,徐州医科大学附属医院眼科

原发性闭角型青光眼白内障超声乳化吸除术房角分离术房角结构参数前节相干光层析成像术

Primary angle closure glaucomaCataractPhacoemulsificationGoniosynechialysisAngle structural parametersAnterior segment-optical coherence tomography

《临床眼科杂志》 2026 (1)

33-39,7

10.3969/j.issn.1006-8422.2026.01.008

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