宫颈HPV感染痰湿体质的中医分析及益气健脾法疗效观察OA
Chinese Medicine Analysis of Phlegm-Damp Constitution in Cervical HPV Infection and Therapeutic Effect of Tonifying Qi and Strengthening Spleen Method
目的 探讨人乳头瘤病毒(human papillomavirus,HPV)感染患者中医体质与证型的相关性,并评估益气健脾祛湿解毒法在痰湿质HPV感染中的疗效及不良反应.方法 分析 2022 年 4 月—2023 年 11 月河南省中医院 1500 例宫颈HPV感染患者的体质,选取400 例痰湿质患者随机分为试验组和对照组(各200 例).对照组给予保妇康栓和重组干扰素α-2b阴道泡腾胶囊治疗,试验组在此基础上加用益气健脾祛湿解毒方.6 个月后记录两组临床疗效、中医证候积分及不良反应.结果 在 1500 例宫颈HPV感染患者中,痰湿质最为常见,且脾虚湿阻证与痰湿质相关性分析显示差异有统计学意义(P<0.05).经过6 个月的治疗,试验组的总有效率为 97%(194/200),而对照组为 90%(180/200).两组治疗效果的差异具有统计学意义(P<0.05).治疗组不良反应发生率低于对照组,无统计学意义(P>0.05).结论 益气健脾祛湿解毒法在痰湿质HPV感染患者中的应用效果显著,有效改善临床症状及不良反应.
Objective To explore the correlation between TCMconstitution and syndrome types in patients with human papillo-mavirus(HPV)infection,and to evaluate the efficacy and side effects of tonifying Qi,strengthening spleen,eliminating damp-ness and relieving toxin method in treating phlegm-damp constitution HPV infection.Methods The constitutions of 1500 patients with cervical HPV infection from April 2022 to November 2023 were analyzed.Among them,400 patients with phlegm-damp constitution were randomly divided into an experimental group and a control group(200 cases in each).The control group was treated with recombinant interferon α-2b vaginal effervescent capsules and Baofukang suppositories alternately.The experimental group received the same treatment with the addition of Yiqi Jianpi Qushi Jiedu Decoction(益气健脾祛湿解毒方).After 6 months,the clinical efficacy,TCMsyndrome scores and side effects were recorded for both groups.Results Among the 1500 pa-tients with cervical HPV infection,phlegm-damp constitution was the most common.The correlation analysis between spleen defi-ciency with dampness obstruction and phlegm-damp constitution showed a statistically significant difference(P<0.05).After 6 months of treatment,the total effective rate was 97%(194/200)in the experimental group and 90%(180/200)in the control group.The difference in treatment efficacy between the two groups was statistically significant(P<0.05).The incidence of side effects in the experimental group was lower than that in the control group,with no statistical significance(P>0.05).Conclusion The tonifying Qi,strengthening spleen,eliminating dampness and relieving toxin method has shown significant efficacy in patients with phlegm-damp constitution HPV infection,effectively improving the clinical symptoms and reducing the side effects.
王海颖;有小娟;赵长普
河南省中医院,河南 郑州 450002河南省中医院,河南 郑州 450002河南省中医院,河南 郑州 450002
医药卫生
宫颈HPV感染中医体质益气健脾祛湿解毒痰湿质
cervical HPV infectionTCMconstitutiontonifying Qi and strengthening spleeneliminating dampness and relie-ving toxinphlegm-damp constitution
《辽宁中医杂志》 2026 (3)
78-81,4
河南省中医药科学研究专项课题(2019ZYBJ12)
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