从"胃滞肠壅,痰瘀蕴毒"探讨动脉粥样硬化的中医病机OA
Discussion on Traditional Chinese Medicine Pathogenesis of Atherosclerosis with Theory of"Stomach Stagnation and Intestinal Obstruction,Accumulation of Phlegm-Stasis-Toxin"
动脉粥样硬化(atherosclerosis,AS)作为病死率居高不下的心血管疾病的重要诱因,严重威胁着人类的健康和生命.防治AS已成为当前医学界研究的热点课题,炎症学说是当前研究AS形成机制的主要理论之一.作者认为"痰瘀毒"是导致AS的重要病因,而胃滞肠壅,气失调达是"痰瘀"生成的前提条件.过食肥甘导致肠道菌群紊乱,代谢失常,血脂、血液流变学发生改变,日久可诱发炎症反应,最终导致AS,该过程与"胃滞肠壅,痰瘀蕴毒"理论相吻合.该文基于"胃滞肠壅,痰瘀蕴毒"理论,探析动脉粥样硬化的中医病机,为临床治疗提供思路.
As an important cause of cardiovascular diseases with high mortality rate,atherosclerosis(AS)is a serious threat to human health and life.The prevention and treatment of AS has become a hot topic in the medical field,and the theory of inflam-mation is one of the main theories to study the formation mechanism of AS.The author believes that"phlegm-stasis-toxin"is an important cause of AS,and stomach stagnation and intestinal obstruction,as well as the inability to regulate Qi,are the prereq-uisite conditions for the generation of"phlegm and blood stasis".Overconsumption of fatty and sweet foods can lead to intestinal flora disturbance,metabolic disorders,abnormal changes in blood lipids,hemorheology and other indicators,which gradually in-duces inflammation and eventually leads to AS.This process is consistent with the theory of"stomach stagnation and intestinal ob-struction,phlegm-stasis-toxin".Based on the theory of"stomach stagnation and intestinal obstruction,accumulation of phlegm-stasis-toxin",this paper analyzed the pathogenesis of AS in traditional Chinese medicine,so as to provide ideas for clinical treat-ment.
成泽东;陈以国
辽宁中医药大学针灸推拿学院,辽宁 沈阳 110847辽宁中医药大学针灸推拿学院,辽宁 沈阳 110847
医药卫生
动脉粥样硬化胃滞肠壅痰瘀蕴毒炎症
atherosclerosisstomach stagnation and intestinal obstructionaccumulation of phlegm-stasis-toxininflammation
《辽宁中医杂志》 2026 (3)
67-69,3
国家自然科学基金项目(82374597)辽宁省应用基础研究计划项目(2022JH2/101300043)辽宁中医药大学自然科学类重点项目(2021LZY037)全国名老中医陈以国教授经验传承工作室(国中医药人教函[2022]75号)
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