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早期开放负压治疗在开放肠道手术高风险伤口中的临床应用OA

Clinical application of early open wound negative pressure therapy in high-risk wounds of open intestinal surgery

中文摘要英文摘要

目的 探讨早期开放伤口负压治疗方案在开放肠道手术高风险伤口中应用的安全性及疗效.方法 回顾性分析2022年6月~2024年8月在南方医科大学珠江医院普通外科行开放肠道手术的57例腹部伤口愈合不良高风险患者的临床资料,其中35例患者术后腹部伤口采用传统换药方法,22例患者实施腹部伤口早期开放负压治疗.比较两组患者伤口愈合时间、换药次数、术后初次下床活动时间、术后初次下床活动舒适度、术后1周疼痛视觉模拟评分、伤口瘢痕评分及伤口愈合不良事件发生率(如脂肪液化、切口感染及肠瘘等).结果 两组患者基线资料的差异均无统计学意义(P>0.05).57例患者腹部伤口均愈合;早期开放负压治疗组在伤口愈合时间、换药次数、伤口愈合不良事件发生率及伤口瘢痕评分均优于传统换药组(P<0.05),两组术后初次下床活动时间、术后初次下床活动舒适度及术后1周疼痛视觉模拟评分的差异无统计学意义(P>0.05).结论 对开放肠道手术腹部伤口愈合不良高风险患者实施早期开放负压治疗,伤口愈合效果确切,外形美观,值得临床推广.

Objective To evaluate the safety and efficacy of an early open wound negative therapy protocol for high-risk wounds after open intestinal surgery.Methods A retrospective cohort study was conducted.Clinical data of 57 abdominal-surgery patients judged to be at high risk for impaired wound healing who underwent open intestinal procedures at the Department of General Surgery,Zhujiang Hospital,Southern Medical University from June 2022 to August 2024 were reviewed.Thirty-five patients received conventional postoperative wound care(standard dressing changes),whereas 22 patients were managed with early open wound negative therapy.The two groups were compared for wound-healing time,number of dressing changes,time to first postoperative ambulation,comfort during first ambulation,1-week postoperative pain(visual analogue scale),scar score,and incidence of adverse wound events(fat liquefaction,surgical-site infection,enterocutaneous fistula,etc.).Results Baseline characteristics did not differ significantly between the groups(P>0.05).All 57 wounds healed.Compared with the conventional-care group,the early open wound negative pressure group showed significantly better outcomes in wound-healing time,number of dressing changes,incidence of adverse wound events,and scar score(P<0.05).No significant differences were observed in time to first ambulation,comfort during first ambulation,or 1-week postoperative pain scores(P>0.05).Conclusion Early open wound negative pressure therapy for high-risk abdominal wounds after open intestinal surgery provides reliable wound healing,is practical to perform,yields superior cosmetic results,and is well accepted by patients;it merits wider clinical adoption.

邹琦;罗桂芝;何玉梅;郑克鸿

南方医科大学珠江医院普外科,广东 广州 510282南方医科大学珠江医院普外科,广东 广州 510282南方医科大学珠江医院普外科,广东 广州 510282南方医科大学珠江医院普外科,广东 广州 510282

腹部伤口愈合不良开放肠道手术开放伤口负压治疗临床实践

poor healing of abdominal woundsopen intestinal surgeryopen wound negative pressure treatmentclinical practice

《分子影像学杂志》 2026 (2)

177-183,7

国家自然科学基金青年基金(82103399)Supported by Natural Science Foundation for the Youth of China(82103399)

10.12122/j.issn.1674-4500.2026.02.06

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